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-
- Description:
- Inter-organelle contact sites have become increasingly appreciated as important regulators of cellular homeostasis, and disruption of inter-organelle contact site dynamics and function has been observed in various pathologies. Recently, inter-organelle contact sites between mitochondria and lysosomes were discovered, offering a new mechanism by which these two organelles may directly interact,...
- Keyword:
- Calcium, Neurological Disease, Mitochondria, Lysosome, Contact Sites, and Imaging
- Subject:
- Medicine, Biology, and Neurosciences
- Creator:
- Peng, Wesley J
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15610 and etdadmin_upload_827420
-
- Description:
- Atrial fibrillation (AF) is the most common cardiac arrhythmia, and associated with increased risk for ischemic stroke and mortality. While the risk of stroke has been shown to be reduced with the use of oral anticoagulants like Warfarin, these medications are predictably linked with an increased risk of bleeding, and...
- Keyword:
- Multidimensional imaging, Atrial fibrillation, Unicuspid aortic valves, Magnetic Resonance Imaging, Cardiac MRI, and 4D flow MRI
- Subject:
- Medical imaging, Engineering, and Biomedical engineering
- Creator:
- Ma, Liliana Esther
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15025 and etdadmin_upload_723481
-
- Description:
- Pathogenic bacteria scavenge essential nutrients including metals, amino acids and peptides to survive within the hostile host environment. Bacteria utilize ATP-binding cassette (ABC) transporters, powered by the energy of ATP hydrolysis, to move substrates across cellular membranes. The substrate-binding protein (SBP) shuttles substrate in the periplasm and directs the substrate...
- Keyword:
- ABC transporters, substrates, peptides, binding proteins, and heme
- Subject:
- Biology and Biophysics
- Creator:
- Tanaka, Kari J
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_640137 and http://dissertations.umi.com/northwestern:14534
-
- Description:
- Sound is one of the most important mediums to understand the environment around us. Identifying a sound event in prerecorded audio (such as a police siren, a dog bark, or a creaking door in soundscapes) leads to a better understanding of the context where the sound events occurred. To do...
- Keyword:
- Sound event detection, Machine learning, Human-in-the-loop interface, Sound event annotation, and Audio signal processing
- Subject:
- Computer science and Artificial intelligence
- Creator:
- Kim, Bongjun
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15064 and etdadmin_upload_739320
-
- Description:
- This dissertation investigates a number of models and algorithms in the context of optimization under uncertainty. The focus is on risk-averse optimization, where risk aversion is modeled via stochastic dominance, utility theory, and distributionally robust optimization. We first investigate an investment model with fixed contribution rates, optimize asset-allocation decisions in...
- Keyword:
- Distributionally robust optimization, Stochastic Programming, and Wasserstein distance
- Subject:
- Operations research
- Creator:
- Duque Villarreal, Daniel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_763341 and http://dissertations.umi.com/northwestern:15241
-
- Description:
- Supported vanadium oxide materials have been extensively studied for alkane oxidative dehydrogenation (ODH) reactions due to their high activity and selectivity. The catalytic activity of supported VOx materials is influenced by the surface coverage of VOx sites and hence the distribution of V=O, V-O-V, and V-O-S (S, support) bonds. The...
- Keyword:
- heterogeneous catalysis, oxidative dehydrogenation, atomic layer deposition, and vanadium oxide
- Subject:
- Chemical engineering
- Creator:
- Samek, Izabela Anna
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14740 and etdadmin_upload_675097
-
- Description:
- Active lateral force feedback is essential for haptic applications in which forces on the fingertip is perpendicular to or in the same direction of finger movement, such as virtual shape rendering and button click rendering. In this thesis, I first present a novel device, the UltraShiver, that can provide large...
- Keyword:
- Active lateral force feedback, Ultrasonic oscillation, Localized control, Shape rendering, Button click rendering, and Electrostatic
- Subject:
- Mechanical engineering
- Creator:
- Xu, Heng
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15498 and etdadmin_upload_800297
-
- Description:
- In recent decades, mass loss from glaciers and ice caps (GICs) worldwide has accelerated, contributing significantly to the observed sea–level rise. Their continued melt is also expected to alter local hydrological systems, affecting freshwater availability and quality. Despite these problematic impacts, little is known about GIC variations prior to the...
- Keyword:
- Glaciers, Arctic, Holocene, and Ice caps
- Subject:
- Climate change, Geographic information science and geodesy, and Limnology
- Creator:
- Larocca, Laura Jennifer
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15847 and etdadmin_upload_861088
-
- Description:
- Increasingly high global energy consumption demands effective approaches to high energy efficiency and, at the same time, paths to reduced release of carbon dioxide, a primary greenhouse gas behind global climate change. Friction reduction is a vital aspect towards making energy systems more efficient and one of the most crucial...
- Keyword:
- tribology, wear, friction, and lubrication
- Subject:
- Mechanical engineering and Materials Science
- Creator:
- Khan, Arman Mohammad
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15582 and etdadmin_upload_819626
-
- Description:
- The investigation of ceria-related materials has a long history since 1920s. The first publication on web of science traces back to 1928. Ever since that, more studies come out and surge starting from 1987. This material has attracted extensive attention due to its wide applications in electrochemical devices, catalysis, and...
- Keyword:
- oxygen vacancy, ceria, redox kinetics, thermochemical fuel production, zirconium, and catalysis
- Subject:
- Materials Science
- Creator:
- Yuan, Weizi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15180 and etdadmin_upload_753575
-
- Description:
- Polyolefins are the most versatile and widely used polymers worldwide. Depending on the polymer microstructure, polyolefins can exhibit a wide range of useful and tailored properties and applications. Metal-catalyzed coordinative olefin polymerization plays a center role in advancing polyolefin synthesis. This dissertation explores two strategies to modulate the polymer microstructures...
- Keyword:
- polar monomer, olefin polymerization, zirconium, bimetallic effect, and scandium
- Subject:
- Inorganic chemistry and Chemistry
- Creator:
- Chen, Jiazhen
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14719 and etdadmin_upload_669232
-
- Description:
- In this thesis I focus on two topics: planet-disk interaction and solar convection. These two seemingly separate topics are connected via a similar separation of timescales. Planets excite spiral waves in their disks on fast timescales compared to the time for the disk to viscously adjust to the angular momentum...
- Keyword:
- planet-disk interaction, protoplanetary disks, convection, accretion disks, exoplanets, and solar physics
- Subject:
- Astrophysics, Computational physics, and Theoretical physics
- Creator:
- Dempsey, Adam
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/28/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14956 and etdadmin_upload_710433
-
- Description:
- This thesis provides an introduction to decay rates for the damped wave equation on compact manifolds. It also gives a proof of a sharp decay rate for solutions to the damped wave equation on the torus with damping of a particular polynomial form. Finally it gives a proof of a...
- Subject:
- Mathematics
- Creator:
- Kleinhenz, Peter Barone
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_764401 and http://dissertations.umi.com/northwestern:15267
-
- Description:
- How we remember, narrate and teach the past is an inherently political and ethical act. This is especially true when teaching about race and racism within the context of United States history. In this dissertation, I ask: how do young people narrate the durability of racial inequality in the United...
- Subject:
- History and Education
- Creator:
- Berry, Allena Ginneh
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15704 and etdadmin_upload_841990
-
- Description:
- Despite its demonstrated effectiveness, exposure therapy – repeatedly approaching a fear/anxiety trigger – is not widely used in the treatment of anxiety disorders. This may be due to its image as an aversive (and even harmful) approach to treatment and its reduced rates of compliance among patients. However, if exposure...
- Keyword:
- courage, anxiety , exposure, fear, and therapy
- Subject:
- Clinical psychology
- Creator:
- Eix, Amanda Kramer
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15630 and etdadmin_upload_831017
-
- Description:
- The product of hexokinase (HK) enzymes, glucose-6-phosphate, can be metabolized through glycolysis or directed to alternative pathways, such as the pentose phosphate pathway (PPP) to generate anabolic intermediates. HK1 contains an N-terminal domain that permits mitochondrial binding, but its physiologic significance remains unclear. We generated mice lacking the HK1 mitochondrial-binding...
- Keyword:
- Macrophage, Subcellular localization, Mitochondria, Inflammation, Metabolism, and Hexokinase
- Subject:
- Biology
- Creator:
- De Jesus, Adam
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_773389 and http://dissertations.umi.com/northwestern:15348
-
- Description:
- Digitization has led to dramatic cost reductions and reshaped both what and how products are sold. This dissertation examines the impact of digitization on the behavior of market intermediaries that bring together producers and consumers. Our empirical context is the transition from 35mm film to digital cinema technologies in the...
- Keyword:
- Digitization, Concentration, and Product Variety
- Subject:
- Economics and Marketing
- Creator:
- Yang, Joonhyuk
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_736303 and http://dissertations.umi.com/northwestern:15056
-
- Description:
- Students pursue educational and career future identities (e.g., graduating college, becoming an engineer, etc.) that are tied to their deepest wants, desires, and needs, yet many find it difficult to exert self-control and resist temptations while pursuing these identities (e.g., studying versus watching TV, paying attention in class versus scrolling...
- Subject:
- Educational psychology
- Creator:
- Svoboda, Ryan C
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14555 and etdadmin_upload_649361
-
- Description:
- This dissertation is a collection of three papers on synthesizing and translating statistical evidence in education research. Chapter 1 serves as an introduction and executive summary, and Chapters 2 - 4 contain the three substantive papers respectively. Chapter 2 presents methods for pooling sample variances across studies to improve properties...
- Keyword:
- meta-analysis, evidence synthesis, translation science, clearinghouse data, data visualization, and statistical cognition
- Subject:
- Statistics and Education
- Creator:
- Fitzgerald, Kaitlyn Grace
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15676 and etdadmin_upload_838471
-
- Description:
- We study modular forms, Jacobi forms, and hermitian formal Fourier-Jacobi series over imaginary quadratic fields. In the first section, we prove that the ring of classical Jacobi forms of a fixed genus g, varying index m and weight k is generated by theta functions. From this result we show that...
- Keyword:
- Algebraic Number Theory, Fourier Jacobi Expansion, and Modular Form
- Subject:
- Mathematics
- Creator:
- Wang, Yuxiang
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15220 and etdadmin_upload_761403
-
- Description:
- Anthropogenic consumption of fossil fuels releases carbon into the Earth-atmosphere-ocean system at rates unmatched by geologic processes. Yet, some geologic time periods also show evidence of climate forcing related to rapid natural greenhouse gas emissions and can serve as tools to help understand the future trajectory of climate. Geologic events...
- Keyword:
- Paleoceanography, Oceanic Anoxic Event 2, Paleocene-Eocene Thermal Maximum, Low-temperature Geochemistry, Ocean acidification, and Climate change
- Subject:
- Paleoclimate science
- Creator:
- Kitch, Gabriella Dawn
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_863458 and http://dissertations.umi.com/northwestern:15871
-
- Description:
- The question of how native species diversity affects a community’s ability to resist invasive species has inspired decades of research. One of the oldest invasion biology hypotheses is that more species rich ecosystems are less invaded. While there has been strong support for this hypothesis, there is also strong evidence...
- Keyword:
- community ecology, ecological restoration, functional diversity, phylogenetic diversity, and invasive species
- Subject:
- Conservation biology, Ecology, and Plant sciences
- Creator:
- Ernst, Adrienne
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15686 and etdadmin_upload_839932
-
- Description:
- Two-dimensional (2D) materials and heterostructures have attracted significant attention for a variety of nanoelectronic and optoelectronic applications. At the atomically thin limit, the material characteristics and functionalities are dominated by surface chemistry and interface coupling. Therefore, methods for comprehensively characterizing and precisely controlling surfaces and interfaces are required to realize...
- Keyword:
- heterostructure, borophene, two dimensional materials, scanning tunneling microscopy, defect, and surface science
- Subject:
- Nanotechnology, Applied physics, and Materials Science
- Creator:
- Liu, Xiaolong
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_622476 and http://dissertations.umi.com/northwestern:14423
-
- Description:
- In this thesis, we aim to develop efficient algorithms with theoretical guarantees for noisy nonlinear optimization problems, with and without constraints, under various different assumptions. Apart from Chapter 1 which provides relevant backgrounds, the remaining of thesis is divided into four chapters. In Chapter 2, we establish the theoretical convergence...
- Keyword:
- BFGS, noisy optimization, quasi-Newton, derivative-free optimization, LBFGS, and nonlinear optimization
- Subject:
- Computer science and Industrial engineering
- Creator:
- Xie, Yuchen
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15749 and etdadmin_upload_844865
-
- Description:
- The purpose of this study was (1) to examine the impact that small ensemble free improvisation experiences had on dispositional empathy development when compared with other forms of collective music making; and (2) to examine the relationship between co-performing musicians’ empathy levels and their performance achievement in small ensembles using...
- Keyword:
- Performance Achievement, Empathy Development, Collective Music Making, and Free Improvisation
- Subject:
- Music education
- Creator:
- Schmidt, Casey
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15692 and etdadmin_upload_840964
-
- Description:
- There is no group of materials as diverse, complex, and ubiquitous as polymers. From plastic bags, to rubber tires, electronics, food packaging, water filtration and even aerospace applications, the penetration of polymer materials into all aspects of life make them very important materials throughout all engineering fields. However, this breadth...
- Keyword:
- Mechanical Properties, Characterization, Composite, Polymer, and Materials Design
- Subject:
- Mechanics, Polymer chemistry, and Materials Science
- Creator:
- Eaton, Matthew David
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15243 and etdadmin_upload_763586
-
- Description:
- Recent advances in combinatorial chemistry, synthetic biology, and ‘omics’ research require high-throughput methods for performing and analyzing thousands to millions of reactions in one day. However, it is a challenge to engineer high-throughput systems that can autonomously conduct and analyze such a large number of reactions in a generalizable and...
- Keyword:
- MALDI Imaging Mass Spectrometry, Microfluidics, Spatiotemporal, Self-assembled monolayers, SAMDI Mass Spectrometry, and Kinetics
- Subject:
- Chemical engineering, Bioengineering, and Chemistry
- Creator:
- Grant, Jennifer
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_625853 and http://dissertations.umi.com/northwestern:14444
-
- Description:
- Brain network organization, the emergence of cognition, and the accumulation of neurodegenerative pathology are interwoven concepts frequently studied under the umbrella of behavioral neurology, neuropsychiatry, neuropsychology, and neuropathology. One approach to studying the organization of cognitive processes is to study those with selective deficits in such networks. To understand how...
- Keyword:
- brain networks, Alzheimer disease, neuroimaging, cortical atrophy, and primary progressive aphasia
- Subject:
- Medical imaging, Pathology, and Neurosciences
- Creator:
- Martersteck, Adam Christopher
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_743337 and http://dissertations.umi.com/northwestern:15111
-
- Description:
- Successful restoration depends on the establishment and survival of selected species, and sowing seed is the most cost-effective method to ensuring a successful restoration. Generally, a locally sourced seed is thought to be better adapted to local environmental conditions and, therefore, more likely to thrive. In addition, a local seed...
- Keyword:
- Germination, Dormancy break, Seedling Establishment, Restoration, and Lespedeza
- Subject:
- Conservation biology
- Creator:
- Hevey, Robert
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15845 and etdadmin_upload_860227
-
- Description:
- Contest theory is an area of game theory that studies environments in which agents make sunk investments in order to get a prize. These investments could be money, effort, time, etc. Contest theory is used to study a wide range of applications, like political contests, research and development, advertisement campaigns,...
- Keyword:
- Game Theory, Contest Theory, All-pay Auctions, and Auctions
- Subject:
- Economics and Economic theory
- Creator:
- Catepillan Tessi, Jorge Francisco
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_626486 and http://dissertations.umi.com/northwestern:14454
-
- Description:
- On 14 January 2017, President Donald J. Trump described the North Atlantic Treaty Organization (NATO) as obsolete. During the first six months of his administration, President Trump discussed not honoring Article 5 commitments for NATO members who had not met the financial responsibilities outlined in the 2014 Wales Summit. His...
- Keyword:
- Collective Action, 21st Century, Theory, Mixed-Methods, and NATO
- Subject:
- Political science
- Creator:
- Dial, Nathan E
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15545 and etdadmin_upload_817491
-
- Description:
- Records of temperature and precipitation during Quaternary interglacial periods on Greenland are notably scarce, limiting assessment of the magnitude and rate of local environmental response to orbitally-driven Arctic warming. It is largely unknown if warming across Greenland was spatially uniform through past interglacials, and if warming was accompanied by major...
- Keyword:
- n-alkanes, n-acids, Hydrogen isotopes, Greenland, Paleoclimate, and Chironomid
- Subject:
- Paleoclimate science
- Creator:
- McFarlin, Jamie Marie
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_661785 and http://dissertations.umi.com/northwestern:14613
-
- Description:
- Research on how sleep contributes to memory has blossomed in recent years. These studies have generally focused on whether or not sleep impacts various types of memory independently. An open question is whether sleep interactively influences different memory types. My research focuses on two types of memory—specificity and generalization. Whereas...
- Keyword:
- generalization, memory, targeted memory reactivation, memory consolidation, and sleep
- Subject:
- Cognitive psychology, Psychobiology, and Neurosciences
- Creator:
- Witkowski, Sarah (Sadie)
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15250 and etdadmin_upload_763727
-
- Description:
- As the global population grows, consumption of water, energy, and food will also increase, placing stresses on these sectors, raising the importance of the Water-Energy-Food Nexus (WEFN). However, operation of WEFN systems are currently not sustainable. It is thus crucial to design WEFN systems to be sustainable from local to...
- Keyword:
- Economics, Modeling, Ecology, Life Cycle Analysis, Optimization, and Sustainability
- Subject:
- Chemical engineering
- Creator:
- Garcia, Daniel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_639822 and http://dissertations.umi.com/northwestern:14526
-
- Description:
- In three empirical chapters, this dissertation examines the field of sustainability over time, specifically uncovering the processes by which contentious interactions between movements and organizations can shift to the development of shared meaning and the creation of new organizational positions. The dissertation utilizes the analyses strategies of text analysis, field...
- Keyword:
- Occupations, Text Analysis, Discourse, Organizations, and Sustainability
- Subject:
- Sociology and Management
- Creator:
- Augustine, Grace L
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_678683 and http://dissertations.umi.com/northwestern:14762
-
- Description:
- In the absence of any significant federal policy to mitigate climate change, many (though not all) U.S. states have stepped in to fill the void. But the policies these states have adopted vary considerably in their quality. For example, California’s economy-wide greenhouse gas policy was significantly stronger than Massachusetts’, which...
- Keyword:
- business power, political sociology, climate and energy policy, business preferences, environmental sociology, and state politics
- Subject:
- Public policy and Environmental law
- Creator:
- Basseches, Joshua
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15219 and etdadmin_upload_761385
-
- Description:
- Uterine leiomyoma (LM), the most common tumor of women, causes severe morbidity. LM cells can be separated into three molecularly and functionally distinct cell populations based on the expression pattern of CD34 and CD49b: stem (LSC, CD34+/CD49b+), intermediate (LIC, CD34+/CD49b-), and differentiated cells (LDC, CD34-/CD49b-). Progesterone via progesterone receptor (PR/PGR)...
- Keyword:
- Uterine leiomyoma, Tumor stem cell, DNA methylation, RANK/RANKL pathway, and Progesterone signaling
- Subject:
- Biology
- Creator:
- Liu, Shimeng
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_722143 and http://dissertations.umi.com/northwestern:15024
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- Description:
- This thesis focuses on the application of neural networks to three types of classification tasks, each work with its own chapter. The objective of the first work is to take advantage of deep neural networks in order to make next day crime count predictions in a fine-grain city partition. We...
- Subject:
- Applied mathematics
- Creator:
- Stec, Alexander Anthony
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_618137 and http://dissertations.umi.com/northwestern:14412
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- Description:
- Store-operated Ca2+ entry (SOCE) is a principal mechanism for generating cellular Ca2+ signals. Store-operated Ca2+ release-activated Ca2+ (CRAC) channels serve an essential role in generating Ca2+ elevations needed for transcriptional, enzymatic, and secretory effector cascades in many cell types. CRAC channels, comprised of the ER Ca2+ sensor STIM and the...
- Subject:
- Biology and Neurosciences
- Creator:
- Toth, Anna
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14766 and etdadmin_upload_679006
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- Description:
- Human complex diseases such as common cancers and diabetes are characterized by high molecular heterogeneity contributed by both genetic and non- genetic factors. This molecular heterogeneity can not only complicate diagnosis, risk stratification and patient care, but also lead to differential therapeutic response and treatment efficiency. Therefore, understanding the molecular...
- Keyword:
- Epigenetics, Complex disease , Cancer , Precision medicine , and Diabetes
- Subject:
- Epidemiology and Bioinformatics
- Creator:
- Zeng, Chang
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_832581 and http://dissertations.umi.com/northwestern:15643
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- Description:
- Non-covalent and ion-specific interactions in the context of charged polymers are ubiquitous in nature and in synthetic applications. For example, mussels utilize metal-coordinate bonds to form tough underwater adhesion to a wide range of substrates. The sandcastle worm uses coacervation of oppositely charged polymers to build robust structures for self-defense....
- Keyword:
- Quartz Crystal Microbalance, Polyelectrolytes, Oil/Water Interface, Coacervate, Coatings, and Polymer Mechanics
- Subject:
- Polymer chemistry and Materials Science
- Creator:
- Sadman, Kazi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_662829 and http://dissertations.umi.com/northwestern:14664
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- Description:
- The structure of the North American crust and mantle was investigated using P wave teleseismic tomography and the links between seismic tomographic models, locations of volcanism, sediment isopachs, and continental scale crustal structures via plate reconstruction modeling. Nearly 50,000 teleseismic P wave delay times were measured from seismograms recorded by...
- Keyword:
- noise spectra, seismic networks, teleseismic, field work, Western Interior Basin, and tomography
- Subject:
- Geology and Geophysics
- Creator:
- Bollmann, Trevor Alan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14783 and etdadmin_upload_682357
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- Description:
- ABSTRACTUnderstanding Micro-macroscopic Phenomena of Tribological Fluids and Surfaces Mechanical power and motion are transmitted through interfaces under contact and relative motion. Friction is inevitable, which can lead to higher operating and energy costs, and severe frictional rubbing can result in material damage and cessation of motion. A deep understanding of...
- Subject:
- Mechanical engineering
- Creator:
- Pickens III, David Bruce
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15405 and etdadmin_upload_780873
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- Description:
- Low-dimensional materials have emerged as a promising platform for ultrathin electronic and optoelectronic devices. The span of electronic properties covers the spectrum from metallic through small and medium bandgap semiconductors to large bandgap insulators, providing all the necessary components to fabricate a variety of devices. Compared to bulk-semiconductor based devices,...
- Keyword:
- Gaussian, antiambipolar, van der Waals heterojunction, self-aligned, low-dimensional materials, and spiking neuron
- Subject:
- Applied physics, Electrical engineering, and Materials Science
- Creator:
- Beck, Megan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/29/2020
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_717678 and http://dissertations.umi.com/northwestern:14986
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- Description:
- This dissertation researches the Cenomanian, Turonian, and Coniacian Stages (100.5 - 86.3 Ma) of the Cretaceous Period, a geologic interval of interest due to its extreme global warmth, iconic faunas, and oceanic anoxic events (OAEs). Five globally dispersed geochemical and stratigraphic case studies reconstruct interactions of the mid-Cretaceous carbon cycle...
- Keyword:
- Cretaceous, Isotope Geochemistry, Sea Level, Ocean Anoxic Events, Greenhouse Climate, and Stratigraphy
- Subject:
- Sedimentary geology, Geology, and Geochemistry
- Creator:
- Jones, Matthew Madden
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_626920 and http://dissertations.umi.com/northwestern:14461
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- Description:
- The effective capture and detoxification of chemical warfare agents (CWAs) is a pressing need in the modern world. Materials are needed for both the destruction of weapon stockpiles and personal protection via fabric coatings or respirators. Attractive candidates for these applications include metal–organic frameworks (MOFs) – highly crystalline materials composed...
- Keyword:
- quantitative structure-activity relationship, hydrolysis, density functional theory, nerve agent, metal−organic framework, and chemical warfare agent
- Subject:
- Chemical engineering, Computational chemistry, and Chemistry
- Creator:
- Mendonca, Matthew Lee
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15063 and etdadmin_upload_739036
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- Description:
- This dissertation is an ethnographic study of the dance makerspace, a learning environment designed to support STEM engagement through making and embodied experience for a group of African American youth dancers. It looks at how participants in a 4-week summer camp program at an urban creative arts center-turned-makerspace, constructed embodied...
- Keyword:
- Dance, STEM, Embodied Cognition, Embodiment, STEAM, and Makerspace
- Subject:
- Science education and Dance
- Creator:
- Champion, Dionne Nicole
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14418 and etdadmin_upload_619548
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- Description:
- This dissertation is a history of religious conservatism between 1880 and the onset of the Great Depression in 1929. Its main argument is that conservative religion in America, rather than being defined by fundamentalism, theological disputes, or cultural antipathy towards pluralism, was an outgrowth of a profound faith in capitalism...
- Keyword:
- Culture Wars, Billy Sunday, Capitalism, Fundamentalism, and Conservatism
- Subject:
- History and Religious history
- Creator:
- Noddings, Timothy Robert
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_657277 and http://dissertations.umi.com/northwestern:14570
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- Description:
- While the entire silicon industry has been blooming under Moore’s Law for decades, conventional digital implementation is approaching the “stall” of Moore’s Law due to many physical design limitations. Technology innovation now is going to take a different direction. Given the increasing demand for emerging applications' computational capacity, it is...
- Keyword:
- mixed-signal time-domain computing, analog computing, machine learning , image processing, computer architecture, and compute in memory (CIM)
- Subject:
- Engineering, Computer engineering, and Electrical engineering
- Creator:
- Chen, Zhengyu
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_780953 and http://dissertations.umi.com/northwestern:15414
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- Description:
- Self-Assembled Monolayers for MALDI-TOF Mass Spectrometry (SAMDI-MS) is a technique that combines self-assembling molecules of alkane disulfides on gold and MALDI-TOF mass spectrometry. By using well-defined monolayers with functionalizations that both prevent non-specific adsorption onto the surface and presents immobilization handles, it is possible to pull out analytes of interest,...
- Keyword:
- SAMDI, MALDI, Data Storage, and Peptides
- Subject:
- Chemistry
- Creator:
- Ten, Alexei Sergeevich
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/29/2020
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_718764 and http://dissertations.umi.com/northwestern:15001