Northwestern University

Parent Unit Name

Login

LIBRARIES | ARCH

Menu Search

Start Over

Filtering by: Keyword Alzheimer's disease Keyword translation Resource type Dissertation Subject Integrated Graduate Program in the Life Sciences

1 entry found

List Gallery Masonry Slideshow

5712m6681?file=thumbnail

1. Energy Deprivation Elevates BACE1 Protein Levels and Promotes Amyloidogenesis via EIF2alpha Phosphorylation

Description:: The cause(s) of Aβ overproduction and accumulation in SAD are unknown; however, several lines of evidence indicate that impaired energy metabolism in the brain may be involved. Furthermore, the rate-limiting enzyme in Aβ production, BACE1, is elevated in SAD brains around amyloid plaques, indicating that BACE1 may also play a...
Keyword:: translation, energy metabolism, BACE1, amyloid, and Alzheimer's disease
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Tracy O'Connor
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/20/2018
Date Modified:: 09/20/2018
Date Created:: 2008-12-04
Resource Type:: Dissertation