Northwestern University

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Microphysiologic Models of Human Ectocervical Tissue to Study Steroid Hormone Action During Homeostasis, Infection, and Oncogenic Transformation

Description:

There is a shortage of research models that adequately represent the unique mucosal environment of human ectocervical tissue, which has limited the development of new therapies for treating infection or cancer. I hypothesized that engineering the microenvironment of ectocervical tissue with in vivo-like endocrine and paracrine support, would enable squamous...

Keyword:

Cervix, Barrier, Differentiation, Mucins, Estradiol, and Progesterone

Subject:

Driskill Graduate Training Program in Life Sciences

Creator:

Kelly Elizabeth McKinnon

Owner:

Scholarly Digital Publishing

Date Uploaded:

04/09/2019

Date Modified:

04/09/2019

Date Created:

2018-01-01

Resource Type:

Dissertation