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Genetic Mechanisms of Benzimidazole Resistance in Caenorhabditis elegans

Description:

Parasitic nematode infections are common in both humans and livestock populations around the globe. In humans, these infections cause illness which can be debilitating. In livestock, parasitic nematode infections result in poor animal health and wellbeing as well as decreases in the yield of these animals. The decrease in yield...

Keyword:

Parasites, Anthelmintics, beta-tubulin, and C. elegans

Subject:

Molecular biology and Genetics

Creator:

Dilks, Clayton Matthew

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

10/07/2021

Date Created:

2021-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15713 and etdadmin_upload_843341
Mechanisms of Acentrosomal Spindle Assembly and Maintenance in C. elegans Oocytes

Description:

Although centrosomes nucleate and organize microtubules in mitotically-dividing cells, spindles in female reproductive cells (oocytes) form in their absence. In some organisms acentrosomal spindle assembly is mediated by acentriolar microtubule organizing centers (MTOCs) that are thought to functionally replace centrosomes. However, spindle assembly in human oocytes does not require MTOCs;...

Keyword:

acentrosomal, meiosis, acentriolar, kinesin, microtubule, and C. elegans

Subject:

Molecular biology, Biochemistry, and Cellular biology

Creator:

Wolff, Ian

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_763687 and http://dissertations.umi.com/northwestern:15248

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Genetic Mechanisms of Benzimidazole Resistance in Caenorhabditis elegans

Mechanisms of Acentrosomal Spindle Assembly and Maintenance in C. elegans Oocytes

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