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Cryogenic-Electron Microscopy Structures of Viral and Eukaryotic Transcription Complexes

Description:

Transcription of nucleic acids (DNA and RNA) is a hallmark of life, taking the information stored within genomic nucleic acids and converting it into a form that is useful for producing the proteins necessary for cellular and organismal function. In eukaryotes, transcription of DNA into messenger RNA (mRNA) requires the...

Keyword:

Virology, Paramyxovirus, Cryo-EM, Mediator, Polymerase, and Transcription

Subject:

Molecular biology, Biochemistry, and Biophysics

Creator:

Abdella, Ryan

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

04/15/2021

Date Created:

2021-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15490 and etdadmin_upload_797897
Structural Studies of the Type III-A CRISPR Effector Complex in Staphylococcus epidermidis RP62a

Description:

Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated Cas proteins provide an immune-like response in many prokaryotes against extraneous nucleic acids. CRISPR-Cas systems are classified into different classes and types that vary widely in composition, target recognition, and overall mechanism. The main division of CRISPR-Cas systems occurs between...

Keyword:

Staphylococcus epidermidis, X-ray crystallography, Cryo-EM, Csm3, CRISPR, and Csm2

Subject:

Molecular biology, Biochemistry, and Biophysics

Creator:

Dorsey, Bryan William

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_655609 and http://dissertations.umi.com/northwestern:14567

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Cryogenic-Electron Microscopy Structures of Viral and Eukaryotic Transcription Complexes

Structural Studies of the Type III-A CRISPR Effector Complex in Staphylococcus epidermidis RP62a

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