Northwestern University

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Filtering by: Keyword DENND1A Keyword rare variants

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Investigation of the Genetic Architecture of Polycystic Ovary Syndrome

Description:

Polycystic ovary syndrome (PCOS) is among the most common endocrine disorders of premenopausal women, affecting 5-15% of this population depending on the diagnostic criteria applied. It is characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. PCOS is highly heritable, but only a small proportion of this heritability can be...

Keyword:

complex trait genetics, rare variants, DENND1A, PCOS, and sub-phenotyping

Subject:

Bioinformatics, Genetics, and Endocrinology

Creator:

Dapas, Matthew

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14662 and etdadmin_upload_662808