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NORMALIZATION OF RNA DEGRADATION IN RNA-SEQ DATA

Description:

RNA-Sequencing (RNA-Seq) is a powerful high-throughput tool to profile transcriptional activities in cells. The observed read counts can be biased by various factors such that they do not accurately represent the true relative abundance of mRNA transcript abundance. Normalization is a critical step to ensure unbiased comparison of gene expression...

Keyword:

Normalization, Matrix factorization, RNA-Seq, and Degradation

Subject:

Statistics

Creator:

Bin Xiong

Owner:

Scholarly Digital Publishing

Date Uploaded:

10/08/2019

Date Modified:

10/08/2019

Date Created:

1/1/2018

Resource Type:

Dissertation