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Investigating MTCH2 as a genetic modifier of cardiomyopathy

Description:

Genetic variation in genes regulating metabolism may be advantageous in some settings but not others. The non-failing adult heart relies heavily on fatty acids as a fuel substrate and source of ATP. In contrast, the failing heart favors glucose as a fuel source. A bootstrap analysis for genes with deviant...

Keyword:

Heart Failure, Glucose, Cardiomyopathy, Drosophila, Metabolism, and Mitochondria

Subject:

Molecular biology, Gender studies, and Cellular biology

Creator:

Fischer, Julie Anne

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/16/2023

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:16326 and etdadmin_upload_941216
MicroRNA MiR-7 Regulation of Insulin-like Peptides in Drosophila

Description:

The insulin/Insulin-Like Growth Factor (IGF) pathway is essential for linking nutritional status to growth and metabolism. MicroRNAs (miRNAs) are short RNAs that are players in the regulation of this process. The miRNA miR-7 shows highly conserved expression in insulin-producing cells across the animal kingdom. However, its conserved functions in regulation...

Keyword:

MicroRNA, Insulin, and Drosophila

Subject:

Molecular biology and Endocrinology

Creator:

Agbu, Pamela

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15272 and etdadmin_upload_764541

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Investigating MTCH2 as a genetic modifier of cardiomyopathy

MicroRNA MiR-7 Regulation of Insulin-like Peptides in Drosophila

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