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Filtering by: 2007-09-26 Keyword Egr Subject Integrated Graduate Program in the Life Sciences

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Description:: The orderly process of hematopoietic differentiation is governed in large part by the coordinated transcription of specific genes. Deregulation of normal differentiation processes can lead to disease states including immunodeficiency, autoimmune disease, and leukemia. This research focuses on the family of transcription factors known as the early growth response (Egr)...
Keyword:: Egr, macrophage, transcription, and thymocyte
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: John Carter
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/12/2018
Date Modified:: 09/12/2018
Date Created:: 2008-05-09
Resource Type:: Dissertation

Description:: Early growth response genes (Egr1-4) are induced as immediate early genes by a variety of extracellular stimuli that influence cellular growth and differentiation. Egr transcriptional regulators modulate gene expression by binding to Egr response elements (ERE) in target genes. In this study, the low affinity p75 neurotrophin receptor (p75NTR) was...
Keyword:: Egr, sympathetic nervous system, dnEgr, neurotrophin signaling, and p75NTR
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Xiaoguang Guo
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/02/2018
Date Modified:: 08/02/2018
Date Created:: 2007-05-31
Resource Type:: Dissertation

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