Posttraumatic stress disorder (PTSD) is an anxiety disorder characterized by flashbacks of the traumatic event and high comorbidity with major depressive disorder (MDD). Prior stress is known to increase the likelihood of developing PTSD after experiencing a traumatic event. Currently, PTSD is diagnosed clinically, its biological etiology is not known...
In humans, posttraumatic stress disorder (PTSD) is co-morbid with major depressive disorder. Individuals who are exposed to stress prior to a traumatic event have an increased likelihood of developing PTSD. To study this increased vulnerability, a rat model was developed using the Stress Enhanced Fear Learning (SEFL) paradigm. This study...