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Filtering by: Keyword Genetics Resource type Dissertation

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The Role of TGF-beta Variants in Breast Cancer

Description:

TGF-β has been named the molecular Jekyll and Hyde of cancer due to its ability to both suppress and promote tumor development. Components of the TGF-β signaling pathway are often mutated in cancer to inhibit the tumor suppressor roles of TGF-β. Our lab studies how a 3-alanine deletion in the...

Keyword:

Biology and Genetics

Subject:

Integrated Graduate Program in the Life Sciences

Creator:

Diana Susan Rosman

Owner:

Scholarly Digital Publishing

Date Uploaded:

10/01/2018

Date Modified:

10/01/2018

Date Created:

2008-10-14

Resource Type:

Dissertation
A microRNA Forms Feedback Loops with Protein Factors and Provides Robustness to Developmental Decisions in the Drosophila Eye

Description:

In the process of development of a multicellular organism, cells must make stable, binary fate decisions in response to intercellular signaling. A critical question is how weak or transient activation of signaling pathways achieves a robust and long-term switch in gene expression, and thus determines cell fate. I report that...

Keyword:

Biology and Genetics

Subject:

Interdepartmental Biological Sciences Program

Creator:

Xin Li

Owner:

Scholarly Digital Publishing

Date Uploaded:

05/07/2018

Date Modified:

05/07/2018

Date Created:

2006-12-04

Resource Type:

Dissertation