In Sub-Saharan Africa, epidemiological studies have reported an increasing burden of non-communicable diseases (NCD) among people living with HIV. NCD management can be feasibly integrated into HIV care; however, clinic readiness to provide NCD services in these settings should first be assessed and gaps in care identified. A cross-sectional survey...
In the United States, African-Americans’ (AAs) HIV infection rates are higher than any other racial group, and AA men who have sex with women (MSW) are a significant proportion of new cases. There is little research into AA MSW HIV/AIDS knowledge, barriers, and facilitators of HIV testing in Chicago. We...
Research suggests that there exists in some homosexual men a moral push towards the disclosure of their HIV serostatus; yet, does an antithetical, individualistic, and self-oriented movement that searches for restitution for HIV infection exist in others? The following study tested the influence of vengeance, hostility, anger, and other negative...
A tetramer model for HIV-1 Integrase (IN) with DNA representing the LTR termini was previously assembled which predicted amino acid residues on the enzyme surface that interact with the LTR termini (Chen et al, 2006). A separate structural alignment of HIV-1, SIV, and ASV INs predicted which of these residues...
Women living with human immunodeficiency virus (WLWH) have unique health challenges. Understanding psychological strengths that help WLWH manage their disease and improve health outcomes could reduce disease burden. Although spirituality, a multidimensional construct that includes a search for meaning and purpose, connection with a higher dimension, and experiences and feelings...
Abstract Kaposi sarcoma (KS) is the most common cancer associated with human immunodeficiency virus/ Acquired Immunodeficiency Syndrome (HIV/AIDS) infection worldwide and it is the most prevalent cancer in some countries in sub-Saharan Africa (SSA). The introduction of combination antiretroviral therapy (ART), led to dramatic declines in KS morbidity and mortality,...
Levels of the several different human apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) cytidine deaminases vary across different cell types. While levels of nuclear-localized A3s are low or non-existent in primary cells, a nuclear A3 is often upregulated in cancer cells. Increased chromosomal mutagenesis due to nuclear A3...