Northwestern University

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ISGF3-Mediated Chromatin Dynamics and Regulation of Type I Interferon-Stimulated Genes

Description:

Type I interferon (IFN) is the primary antiviral cytokine establishing a broad and potent antiviral response to protect mammalian cells from virus infection. The functional repertoire of IFN extends to innate and adaptive immunity, neoplastic transformation, resistance and cancer immunotherapy. IFN functions are primarily mediated through the Janus kinase (JAK)...

Keyword:

ISGF3, Interferon, Chromatin, Antiviral, ISG, and H2A.Z

Subject:

Virology, Molecular biology, and Cellular biology

Creator:

Au Yeung, Weng Si (Nancy)

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2018-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_618020 and http://dissertations.umi.com/northwestern:14409