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Enabling cell-based therapies through environmental sensing and signal processing

Description:

Cell-based therapies are an exciting frontier in medicine. This field is built on a simple premise—cells can be engineered to recognize and treat various human diseases. The paradigm of cell-based therapy uses biosensors to interrogate a cell’s environment and distinguish disease from health, intracellular signaling pathways and genetic circuitry to...

Keyword:

Cell-based therapy, Synthetic receptors, Synthetic biology, Biosensors, Transcription factors, and Immunotherapy

Subject:

Bioengineering, Biology, and Medicine

Creator:

Donahue, Patrick Sean

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Modified:

05/06/2022

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15420 and etdadmin_upload_781062
Steps Toward Engineering the Immune System: Understanding Lymphoid Cell Regulation in the Intestine

Description:

Intestinal immunity is a critical contributor to host health. The immune system in the intestine maintains both defense against pathogens and homeostasis of intestinal tissue, which is exposed to environmental influences, including microbes and ingested foods. Proper regulation of the immune response is required to prevent damage to the host....

Keyword:

Bioengineering, Host-Microbiome, Regulation, Immunotherapy, and Immunity

Subject:

Bioengineering, Medicine, and Immunology

Creator:

Bostick, John

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_661070 and http://dissertations.umi.com/northwestern:14597

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Enabling cell-based therapies through environmental sensing and signal processing

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