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Genome-wide identification of shared and strain-specific factors necessary for Klebsiella pneumoniae enteric colonization

Description:

Gastrointestinal (GI) colonization by Klebsiella pneumoniae is a risk factor for subsequent infection as well as transmission to other patients. Additionally, colonization is achieved by many strain types that exhibit high diversity in genetic content. However, how K. pneumoniae achieves colonization and whether the genetic factors it uses differ by...

Keyword:

Klebsiella pneumoniae, Genomics, Transposon mutant screen, and Gastroinestinal colonization

Subject:

Microbiology and Medicine

Creator:

Cheung, Bettina

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

08/23/2023

Date Created:

2023-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:16716 and etdadmin_upload_1012335
Identification and Characterization of Strain Dominance During Mixed-Strain Pneumonias

Description:

While microbial competition during infection has most often been examined at the genus or species level [1, 2], the dissertation work described herein asked whether interstrain competition plays an important role in determining which bacterial lineages emerge to cause disease. The goal of this dissertation was to examine the strain...

Keyword:

Klebsiella pneumoniae, Pneumonia, Strain Identification, StrainSeq, and Acinetobacter baumannii

Subject:

Microbiology and Immunology

Creator:

Agard, Mallory

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14551 and etdadmin_upload_647535

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Genome-wide identification of shared and strain-specific factors necessary for Klebsiella pneumoniae enteric colonization

Identification and Characterization of Strain Dominance During Mixed-Strain Pneumonias

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