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- Description:
- The assembly of nanoscale building blocks into larger ensembles with well-defined architecture has the potential to create entirely new classes of designer photonic and plasmonic metamaterials with unique properties not found in nature. Electromagnetic metasurfaces, or 2D metamaterials, operating at optical wavelengths are of particular interest due to ease of...
- Keyword:
- Directed Assembly, Electron Microscopy, Nanotechnology, Nanoparticles, Self-Assembly, and Nanopatterning
- Subject:
- Materials Science and Engineering
- Creator:
- BENJAMIN MYERS
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 10/08/2019
- Date Modified:
- 10/08/2019
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
-
- Description:
- This project is comprised of primary source research on the field of semiconductor microscopy. We were interested in determining a more interdisciplinary application of this technology, as the most frequently cited applications are for defense purposes such as drug screening or infrared imaging. When we researched, we found that these...
- Keyword:
- Terahertz Spectroscopy, Semiconductors, Lasers, and Nanotechnology
- Subject:
- Electrical Engineering
- Creator:
- Vivian Chen and Nathaniel Coirier
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 06/03/2019
- Date Modified:
- 06/03/2019
- Date Created:
- 3/22/2019
-
- Description:
- The projected increase in the use of nanomaterials raises concerns about adverse impacts new technologies utilizing these materials may have on the environment. These concerns can be addressed from a chemical perspective by studying how emerging nanomaterials interact with biological systems. Fundamentally, the key interactions for nanomaterial uptake into a...
- Keyword:
- Sustainable, Nanotechnology, Polymers, Nano/Bio, and Biomimetic
- Subject:
- Chemistry
- Creator:
- Alicia McGeachy
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 04/09/2019
- Date Modified:
- 04/09/2019
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
-
- Description:
- Plasmonic nanostructures are capable of trapping and confining light at the nanoscale, leading to interesting optical phenomena involving enhanced light-matter interactions. These responses arise in two forms: surface plasmon polaritons propagating on the surface of metal films and localized surface plasmons confined to the surface of metal nanoparticles. Plasmonic modes...
- Keyword:
- Plasmonics, Nanotechnology, Symmetry, Nanopatterning, Nanofabrication, and Lasers
- Subject:
- Materials Science and Engineering
- Creator:
- Michael Knudson
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 02/25/2019
- Date Modified:
- 02/25/2019
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
-
- Description:
- Spinal cord injury occurs with a worldwide incidence of 13-33 cases per million per year, and more than 2.5 million patients worldwide suffer from spinal cord injury (SCI)-related disability (1, 2). Different methods have been attempted to promote axonal regeneration, including neurotrophin injection, hydrogel injection, olfactory ensheathing cells implantation and...
- Keyword:
- Nanotechnology, Therapeutics, Cord Injury, and Fibrosis
- Subject:
- Driskill Graduate Training Program in Life Sciences
- Creator:
- Suji Jeong
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 02/08/2019
- Date Modified:
- 02/09/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- X-ray Fluorescence Microscopy (XFM) is a useful technique for study of biological samples. XFM was used to map and quantify endogenous biological elements as well as exogenous materials in biological samples, such as the distribution of titanium dioxide (TiO2) nanoparticles. TiO2 nanoparticles are produced for many different purposes, including development...
- Keyword:
- Nanotechnology, Radiation Oncology, Cancer Nanotechnology, and Xray Fluorescence Microscopy
- Subject:
- X-ray Fluorescence Microscopy (XFM) is a useful technique for study of biological samples. XFM was used to map and quantify endogenous biological elements as well as exogenous materials in biological samples, such as the distribution of titanium dioxide (TiO2) nanoparticles. TiO2 nanoparticles are produced for many different purposes, including development of therapeutic and diagnostic particles for cancer detection and treatment, drug delivery, and induction of DNA breaks. Delivery of such nanoparticles can be targeted to specific cells and subcellular structures. In this work, we develop two novel approaches to stain TiO2 nanoparticles for optical microscopy and to confirm that staining by XFM. The first approach utilizes fluorescent biotin and fluorescent streptavidin to label the nanoparticles before and after cellular uptake; the second approach is based on the copper-catalyzed azide–alkyne cycloaddition, the so-called CLICK chemistry, for labeling of azide conjugated TiO2 nanoparticles with “clickable” dyes such as alkyne Alexa Fluor dyes with a high fluorescent yield. To confirm that the optical fluorescence signals of nanoparticles stained in situ match the distribution of the Ti element, we used high resolution synchrotron X-Ray Fluorescence Microscopy (XFM) using the Bionanoprobe instrument at the Advanced Photon Source at Argonne National Laboratory. Titanium-specific X-ray fluorescence showed excellent overlap with the location of Alexa Fluor optical fluorescence detected by confocal microscopy. In this work XFM was also used to investigate native elemental differences between two different types of head and neck cancer, one associated with human papilloma virus infection, the other virus free. Future work may see a cross between these themes, for example, exploration of TiO2 nanoparticles as anticancer treatment for these two different types of head and neck cancer
- Creator:
- Koshonna Brown
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/25/2019
- Date Modified:
- 01/25/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Nanoscale materials are demonstrating new properties and promising applications with each passing day. The fabrication of ever more complex and precise nanomaterials represents a continuing drive in the fields of physics, chemistry, and biology. Template-based approaches provide an attractive method of producing new inaccessible materials by modifying and confining older...
- Keyword:
- Nanoparticles, Nanotechnology, Nanowells, and Tantalum Oxide
- Subject:
- Chemistry
- Creator:
- Jeremy Barton
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 09/10/2018
- Date Modified:
- 09/10/2018
- Date Created:
- 2008-05-12
- Resource Type:
- Dissertation
-
- Description:
- Novel materials and nanostructures with superior electro-mechanical properties are emerging in the development of novel devices. Engineering application of these materials requires accurate electro-mechanical characterization, which in turn requires development of novel experimental techniques. This dissertation outlines the investigation of the mechanical and electrical properties of one-dimensional nanomaterials. One-dimensional nanomaterials...
- Keyword:
- MEMS, Nanotechnology, Thin Film, Nanomaterial, and Mechanical Property
- Subject:
- Mechanical Engineering
- Creator:
- Bei Peng
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 09/07/2018
- Date Modified:
- 09/07/2018
- Date Created:
- 2008-05-09
- Resource Type:
- Dissertation
-
- Description:
- Metal and bimetallic nanoparticles are of interest and are widely used in various applications because of their unique optical, electronic, and catalytic properties, which differ from those of their bulk counterparts. Better understanding of the thermodynamic and kinetic properties of nanoparticles and their underlying growth mechanisms can serve as a...
- Keyword:
- Electron Microscopy, Nanotechnology, and Materials Chemistry
- Subject:
- Materials Science and Engineering
- Creator:
- Lingxuan Peng
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 03/28/2018
- Date Modified:
- 03/28/2018
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- The ability to track labeled cancer cells in vivo would allow researchers to study their distribution, growth and metastatic potential within the intact organism. Magnetic Resonance (MR) imaging is invaluable for tracking cancer cells in vivo as it benefits from high spatial resolution and absence of ionizing radiation. However, many...
- Keyword:
- Nanotechnology and Chemistry
- Subject:
- Interdepartmental Biological Sciences (IBiS) Graduate Program
- Creator:
- Nikhil Ram Mohan
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 02/20/2018
- Date Modified:
- 02/20/2018
- Date Created:
- 2016-01-01
- Resource Type:
- Dissertation