Index Catalog // Arch : Northwestern University Institutional Repository

Recurrent inhibition within olfactory networks shapes noise correlations and stimulus discrimination

Description:: Each second, living organisms take in sensory input from an ever-changing environment and respond appropriately. Identifying and contextualizing stimuli is critical for survival, and it often necessitates distinguishing between sensory experiences that are similar to each other. Pattern separation characterizes the mechanisms by which neuronal networks extract and highlight differences...
Keyword:: Sensory processing, Neuroscience, and Olfaction
Subject:: Applied mathematics
Creator:: Wang, Angelia Feiyang
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/16/2023
Date Created:: 2022-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_945895 and http://dissertations.umi.com/northwestern:16353

Intrinsic Properties Shape Feature Selectivity in Retinal Ganglion Cells

Description:: The retina does not act as a simple camera, rather visual information goes through multiple layers of processing before it reaches the brain. Retinal ganglion cells (RGCs) are the output neurons of the retina and process visual information in the retina and then project into the brain. There are over...
Keyword:: Vision, Retinal ganglion cells, Neuroscience, and Retina
Subject:: Neurosciences
Creator:: Wienbar, Sophia Rose
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 06/22/2022
Date Created:: 2022-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:16017 and etdadmin_upload_898849

IMPLANTABLE OPTOGENETIC DEVICES FOR BROAD NEUROSCIENCE RESEARCH

Description:: Recent development on optogenetic methods offers reliable path to modulate cell activities with high level spatiotemporal precision. Application of this technology in behavior studies significantly improves our understanding in the neural principle that underpin animal behaviors, including ourselves. Full exploitation of optogenetic method in neuroscience behavior studies relies on...
Keyword:: Wireless, Neuroscience, Optogenetics, Robotics, and Battery-free
Subject:: Engineering
Creator:: Yang, Yiyuan
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 06/28/2021
Date Created:: 2021-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_815460 and http://dissertations.umi.com/northwestern:15529

Rat Whisker Mechanics for Neuroscience and Bio-Inspired Sensors

Description:: Research on rat whiskers offers knowledge in neuroscience analogous to humans\' sense of touch and inspiration for efficient sensing robotics. The present work investigates the rat whisker system from a mechanical engineering perspective. First, key quasi-static and dynamic properties were quantified in Chapter 2 for individual whiskers in an array,...
Keyword:: Mechanics, Wearable sensor, Neuroscience, Rat Whisker, and Bio-inspired robotics
Subject:: Mechanical Engineering
Creator:: En-Tzu Yang
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/30/2019
Date Modified:: 09/30/2019
Date Created:: 1/1/2018
Resource Type:: Dissertation

Machine learning approaches towards understanding movement planning in naturalistic settings

Description:: A central question in neuroscience is how the brain plans movements. Here, I apply neural data analysis and machine learning methods to better understand both eye and arm movement planning, in particular focusing on naturalistic settings. First, I built encoding models to investigate the factors that led to neural activity...
Keyword:: Frontal Eye Field, Generalized Linear Model, Saccade, Neuroscience, Premotor Cortex, and Machine Learning
Subject:: Interdepartmental Neuroscience Program (NUIN)
Creator:: Joshua I Glaser
Owner:: Scholarly Digital Publishing
Date Uploaded:: 02/22/2019
Date Modified:: 02/22/2019
Date Created:: 2018-01-01
Resource Type:: Dissertation

The Behavioral and Neural Basis for the facilitation of Insight Problem-Solving by a Positive Mood

Description:: Previous research has shown that creative insight problem-solving is distinct from systematic analytical problem-solving. Behaviorally, a positive mood has shown to facilitate insights but without knowing the processes that are fundamental to insight, the mechanisms as to how a positive mood facilitates insights have remained unspecified. Here, we investigate the...
Keyword:: Neuroscience and Biology
Subject:: Neuroscience Institute Graduate Program
Creator:: Karuna Subramaniam
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/02/2018
Date Modified:: 10/02/2018
Date Created:: 2008-12-05
Resource Type:: Dissertation

The influence of age on the neurophysiologic and neurobehavioral response to sleep deprivation and subsequent recovery

Description:: Sleep deprivation (Sd) preferentially impairs predictive and adaptive behaviors that shift responses based on the appropriate context. Behavioral studies implicate the frontal lobes as particularly susceptible to Sd. Aging also impairs frontal functioning, and alters the response to Sd. The interaction between age and Sd is poorly understood, and few...
Keyword:: Sleep deprivation, Cognition, Neuroscience, Recovery Sleep, Sleep, and Aging
Subject:: Neuroscience Institute Graduate Program
Creator:: Bryce Anthony Mander
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/02/2018
Date Modified:: 10/02/2018
Date Created:: 2008-12-08
Resource Type:: Dissertation

Synaptic integration in excitable CA1 pyramidal neuron dendrites

Description:: A pyramidal neuron receives thousands of inputs spread throughout its dendritic tree, which it must integrate into a decision about whether or not to fire action-potential output. Since action potentials are the primary means by which these neurons communicate with their network partners, understanding this input-output relationship is critical for...
Keyword:: Neuroscience and Biology
Subject:: Interdepartmental Biological Sciences Program
Creator:: Yael Katz
Owner:: Jason Christ Chandra
Date Uploaded:: 09/16/2018
Date Modified:: 09/16/2018
Date Created:: 2008-07-29
Resource Type:: Dissertation

Trafficking mechanism of H channels in CA1 pyramidal neurons and its implication in the pathophysiology of temporal lobe epilepsy

Description:: Many ion channels are localized in specific subcellular domain of the neurons, and the proper localization is critical for the function of ion channels. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels (h channels) are asymmetrically distributed in the CA1 pyramidal neurons, enriched in the distal apical dendrites. H current, generated by h...
Keyword:: Neuroscience and Biology
Subject:: Neuroscience Institute Graduate Program
Creator:: Minyoung Shin
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/27/2018
Date Modified:: 08/27/2018
Date Created:: 2007-12-07
Resource Type:: Dissertation

The Actin-Based Motility Machinery of Neuronal Growth Cone Veils.

Description:: The growth cone is a highly specialized motile structure with a distinctive and dynamically variable morphology. Current understanding of actin-based protrusive motility has been formulated in terms of the dendritic nucleation/array treadmilling model for lamellipodial protrusion and the convergent-elongation model for filopodial protrusion, that were based upon results obtained primarily...
Keyword:: Neuroscience and Biology
Subject:: Neuroscience Institute Graduate Program
Creator:: Anne Katherine Mongju
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/27/2018
Date Modified:: 08/27/2018
Date Created:: 2007-07-30
Resource Type:: Dissertation

Mechanisms Underlying Response Suppression in Cat Visual Cortex

Description:: A comprehensive understanding of how image processing occurs in the primary visual cortex (V1) requires learning what aspects of neuronal responses are driven by strong feed-forward input from the lateral geniculate nucleus (LGN), and what aspects arise due to the densely recurrent network operating within the cortex itself. From an...
Keyword:: Neuroscience and Biology
Subject:: Neuroscience Institute Graduate Program
Creator:: Ian Micah Finn
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/16/2018
Date Modified:: 08/16/2018
Date Created:: 2007-10-22
Resource Type:: Dissertation

Studies of the Homeostatic and Metabolic Regulation of GnRH Pulse Generator

Description:: Gonadotropin releasing hormone (GnRH) neurons comprise the final pathway through which the central nervous system exerts its control over the hypothalamic-pituitary-gonadal (HPG) axis. GnRH is released in a pulsatile manner, and conveyed to the anterior pituitary gland to stimulate synthesis and secretion of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating...
Keyword:: Neuroscience and Biology
Subject:: Neuroscience Institute Graduate Program
Creator:: Wenyu Huang
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/06/2018
Date Modified:: 08/06/2018
Date Created:: 2007-06-21
Resource Type:: Dissertation

Validating Dissociations between Human Memory Subtypes: Conceptual Priming, Familiarity, and Recollection

Description:: A comprehensive understanding of human memory requires both cognitive and neural descriptions of memory processes along with a conception of how memory processing drives behavioral responses and subjective experiences. Noninvasive neuroimaging techniques have greatly extended our understanding of the functional characteristics of human memory, and how neural events give rise...
Keyword:: Neuroscience and Biology
Subject:: Neuroscience Institute Graduate Program
Creator:: Joel Lawrence Voss
Owner:: Scholarly Digital Publishing
Date Uploaded:: 06/05/2018
Date Modified:: 06/05/2018
Date Created:: 2007-05-11
Resource Type:: Dissertation

Cholinergic Regulation of Corticostriatal Signaling in Striatal Medium Spiny Neurons and Cellular Adaptation Following Dopamine Depletion

Description:: Information processing in the striatum is crucial for voluntary movement control and associative learning and in the normal condition is subject to balanced dopaminergic and cholinergic modulation. However, in Parkinson's disease (PD) striatal dopamine (DA) level falls because of degeneration of DA neurons in the substantia nigra pars compacta and...
Keyword:: Neuroscience
Subject:: Neuroscience Institute Graduate Program
Creator:: Jun Ding
Owner:: Scholarly Digital Publishing
Date Uploaded:: 05/28/2018
Date Modified:: 05/28/2018
Date Created:: 2007-05-10
Resource Type:: Dissertation

S6K1 Inhibition-Mediated Changes in Motoneuron Properties in a Mouse Model of Amyotrophic Lateral Sclerosis

Description:: Amyotrophic lateral sclerosis (ALS) is characterized by progressive motoneuron loss. Autopsy from thoracic spinal tissues of sALS patients revealed a significant loss of large motoneurons while medium and small motoneurons were relatively unaffected. Using two-photon microscopy, we observed a soma hypertrophy of neonatal motoneurons in mice overexpressing mutant human G93A-superoxide...
Keyword:: Accounting and Neuroscience
Subject:: Interdepartmental Neuroscience Program (NUIN)
Creator:: Su-Wei Kuo
Owner:: Scholarly Digital Publishing
Date Uploaded:: 02/27/2018
Date Modified:: 02/27/2018
Date Created:: 2017-01-01
Resource Type:: Dissertation

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Recurrent inhibition within olfactory networks shapes noise correlations and stimulus discrimination

Intrinsic Properties Shape Feature Selectivity in Retinal Ganglion Cells

IMPLANTABLE OPTOGENETIC DEVICES FOR BROAD NEUROSCIENCE RESEARCH

Rat Whisker Mechanics for Neuroscience and Bio-Inspired Sensors

Machine learning approaches towards understanding movement planning in naturalistic settings

The Behavioral and Neural Basis for the facilitation of Insight Problem-Solving by a Positive Mood

The influence of age on the neurophysiologic and neurobehavioral response to sleep deprivation and subsequent recovery

Synaptic integration in excitable CA1 pyramidal neuron dendrites

Trafficking mechanism of H channels in CA1 pyramidal neurons and its implication in the pathophysiology of temporal lobe epilepsy

The Actin-Based Motility Machinery of Neuronal Growth Cone Veils.

Mechanisms Underlying Response Suppression in Cat Visual Cortex

Studies of the Homeostatic and Metabolic Regulation of GnRH Pulse Generator

Validating Dissociations between Human Memory Subtypes: Conceptual Priming, Familiarity, and Recollection

Cholinergic Regulation of Corticostriatal Signaling in Striatal Medium Spiny Neurons and Cellular Adaptation Following Dopamine Depletion

S6K1 Inhibition-Mediated Changes in Motoneuron Properties in a Mouse Model of Amyotrophic Lateral Sclerosis

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