Index Catalog // Arch : Northwestern University Institutional Repository

Description:: The brains of humans and animals have the amazing capability of extracting abstract relationships between external stimuli efficiently. Knowing such regularities helps us compute and react to novel information flexibly without prior experience. The olfactory system is no exception. Animals need to infer commonalities across different odors sharing similar meaning,...
Keyword:: Neurosciences
Subject:: Interdepartmental Neuroscience Program (NUIN)
Creator:: Xiaojun Bao
Owner:: Scholarly Digital Publishing
Date Uploaded:: 11/04/2019
Date Modified:: 11/04/2019
Date Created:: 2018-01-01
Resource Type:: Dissertation

Description:: Mounting evidence indicates that known schizophrenia susceptibility genes regulate dendritic spines supports the model that perturbations in the molecular network underlying spine plasticity are crucially involved in the pathogenesis of schizophrenia. The Rac1- and RhoA-guanine nucleotide exchange factor (GEF) kalirin is critical for spine morphogenesis on cortical pyramidal neurons, and...
Keyword:: Neurosciences
Subject:: Interdepartmental Neuroscience Program (NUIN)
Creator:: THERON ANDREW RUSSELL
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/08/2019
Date Modified:: 10/08/2019
Date Created:: 2018-01-01
Resource Type:: Dissertation

Description:: The form and function of neural circuits are shaped by experience during critical periods of development. Recently, our lab discovered an important outcome of critical period plasticity in the visual system, namely, binocular matching of orientation preference, whereby initially randomly aligned orientation preferences become matched in individual cells. Following this...
Keyword:: Neurosciences
Subject:: Interdepartmental Neuroscience Program (NUIN)
Creator:: Jared Nathan Levine
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/09/2018
Date Modified:: 10/09/2018
Date Created:: 2017-01-01
Resource Type:: Dissertation

Description:: The over-a-decade quantitative study of the flexion synergy has provided concrete evidence that the stereotypical movement coupling of shoulder abduction with elbow flexion and wrist/finger flexion (i.e. flexion synergy) significantly affects the ability to perform functional upper extremity movements that are essential for activities of daily living (e.g. reach-to-grasp an...
Keyword:: Neurosciences
Subject:: Interdepartmental Neuroscience Program (NUIN)
Creator:: Yiyun Lan
Owner:: Scholarly Digital Publishing
Date Uploaded:: 04/26/2018
Date Modified:: 04/26/2018
Date Created:: 2017-01-01
Resource Type:: Dissertation

Description:: Kainate receptors (KARs) are expressed throughout the central and peripheral nervous systems. One of three subfamilies of ionotropic glutamate receptors, KARs are localized both pre- and post-synaptically and exert important modulatory control over neural circuits. This modulatory role in circuit function makes them a potential actor in wide variety of...
Keyword:: Neurosciences
Subject:: Driskill Graduate Training Program in Life Sciences
Creator:: Claire Vernon
Owner:: Scholarly Digital Publishing
Date Uploaded:: 03/13/2018
Date Modified:: 03/13/2018
Date Created:: 2017-01-01
Resource Type:: Dissertation

Description:: Fetal alcohol spectrum disorder (FASD), the result of fetal alcohol exposure (FAE), affects 2-11% of children worldwide with no treatments in sight. In my thesis work, I aimed to identify underlying biological mechanisms of the FAE-induced hippocampus-based cognitive deficits that would lead to identify potential treatment targets to reverse the...
Keyword:: Neurosciences
Subject:: Interdepartmental Neuroscience Program (NUIN)
Creator:: Elif Tunc-Ozcan
Owner:: Scholarly Digital Publishing
Date Uploaded:: 03/12/2018
Date Modified:: 03/12/2018
Date Created:: 2017-01-01
Resource Type:: Dissertation

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