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Apolipoprotein Proteoforms and Their Association with Cardiovascular Metabolism

Description:

Despite prevention and treatment, substantial risk for cardiovascular disease(CVD) remains in the population and CVD has been the leading global cause-of-death in past years.While high-density lipoprotein (HDL) markers such as HDL cholesterol (HDL-C) and HDL efflux (a cholesterol-transport-function assay) are associated with decreased risk of CVD, the mechanism of this...

Keyword:

Cardiovascular Disease, Apolipoproteins, Post-translational Modifications, Proteoforms, and Top-down Proteomics

Subject:

Chemistry

Creator:

dos Santos Seckler, Henrique

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

04/15/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_791345 and http://dissertations.umi.com/northwestern:15443
Interrogation of the Proteoform Landscape of Immune Activation after Organ Transplantation: Translational Top-Down Proteomics for Next-Generation Diagnostics and Personalized Medicine

Description:

What follows is a strictly post-genomic dissertation. Over the past five years, I have strived to leave the nucleus behind, and even the endoplasmic reticulum and golgi apparatus. The human genome was sequenced over 15 years before the submission of this document, and the world changed somewhat less than anticipated—besides...

Keyword:

Top-Down Proteomics, Proteomics, Transplantation, Immunology, Mass Spectrometry, and Proteoforms

Subject:

Interdepartmental Biological Sciences (IBiS) Graduate Program

Creator:

Tinothy Toby

Owner:

Scholarly Digital Publishing

Date Uploaded:

01/25/2019

Date Modified:

01/25/2019

Date Created:

2017-01-01

Resource Type:

Dissertation

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Apolipoprotein Proteoforms and Their Association with Cardiovascular Metabolism

Interrogation of the Proteoform Landscape of Immune Activation after Organ Transplantation: Translational Top-Down Proteomics for Next-Generation Diagnostics and Personalized Medicine

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