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Description:
Advances in biosensor engineering have enabled the design of programmable molecular systems to detect a range of pathogens, nucleic acids, and chemicals. Here, we engineer and field-test a biosensor for fluoride, a major groundwater contaminant of global concern. The sensor consists of a cell-free system containing a DNA template that...
Keyword:
Diagnostic Fluoride Riboswitch Cell-Free Synthetic Biology Subject:
Synthetic Biology Diagnostics Creator:
Nancy Kelley-Loughnane Matthew S. Verosloff Michael C. Jewett Walter Thavarajah Julius B. Lucks Adam D. Silverman Contributor:
This work was supported by the Air Force Research Laboratory Center of Excellence for Advanced Bioprogrammable Nanomaterials (C-ABN) Grant FA8650-15-2-5518 (to M.C.J. and J.B.L), the David and Lucile Packard Foundation (to M.C.J.), an NSF CAREER Award (1452441 to J.B.L.), and the Camille Dreyfus Teacher-Scholar Program (to M.C.J. and J.B.L.). A.D.S. was supported in part by the National Institutes of Health Training Grant (T32GM008449) through Northwestern University’s Biotechnology Training Program. Owner:
Julius Beau Lucks Language:
English Date Uploaded:
06/18/2019
Date Modified:
01/08/2020
Date Created:
2019-06-04 Resource Type:
Dataset Alternate Identifier:
https://doi.org/10.21985/N2RJ64