Zebrafish (Danio rerio) are heavily studied because they share a similar genetic structure to humans. The skin patterns of zebrafish are comprised of horizontal stripes of different colored pigment cells. Accurately quantifying the cell size of various pigment cells in relation to their location on the skin is a crucial...
The T-box transcription factor, Tbx5, is involved in heart development and congenital disease. For example mutations in human TBX5 lead to Holt-Oram syndrome, a disease characterized by a range of heart and arm malformations. Tbx5 gene activity has been perturbed in several animal models including the chicken, mouse, and zebrafish....