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Src Family Kinase Phosphorylation of the Motor Domain of the Human Kinesin-5, Eg5

Description:

Spindle formation in mammalian cells requires precise spatial and temporal regulation of the kinesin-5 motor proteins which generate outward force to establish spindle bipolarity. A growing body of work suggests that phosphorylation of kinesin-5 motor domains is an important regulator of their motor characteristics and function in cells. My thesis...

Keyword:

mitosis,, kinesin-5, cytoskeleton, phosphorylation, Src family kinases, and drug resistance

Subject:

Driskill Graduate Training Program in Life Sciences

Creator:

Kathleen Gifford Bickel

Owner:

Scholarly Digital Publishing

Date Uploaded:

10/12/2018

Date Modified:

10/12/2018

Date Created:

2017-01-01

Resource Type:

Dissertation
Plakophilin 2: Critical Roles in Intercellular Junction Assembly and Maturation via Regulation of Protein Kinase C and Actin

Description:

Desmosomes are adhesive complexes found at sites of intercellular contact that are essential for mediating cell-cell adhesion. These junctions undergo regulated assembly and reorganization during processes such as embryogenesis and wound healing. Plakophilins (PKPs) are armadillo family members related to the classic cadherin-associated protein p120ctn. PKPs localize to the cytoplasmic...

Keyword:

desmosome, cytoskeleton, cell-cell adhesion, armadillo, and plakophilin

Subject:

Integrated Graduate Program in the Life Sciences

Creator:

Amanda Elisabeth Bass-Zubek

Owner:

Scholarly Digital Publishing

Date Uploaded:

09/20/2018

Date Modified:

09/20/2018

Date Created:

2008-09-18

Resource Type:

Dissertation

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Src Family Kinase Phosphorylation of the Motor Domain of the Human Kinesin-5, Eg5

Plakophilin 2: Critical Roles in Intercellular Junction Assembly and Maturation via Regulation of Protein Kinase C and Actin

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