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Developing Immunotherapy Targeting Immune Suppression Using Spherical Nucleic Acids (SNAs)

Description:

Cancer remains a leading cause of death worldwide, necessitating continued study to explore and unravel its complex etiology. For example, there has been a shift of focus in cancer treatment from surgery and radiotherapy to targeted chemo- and immunotherapies as we gain more knowledge on the hallmarks of cancer (e.g.,...

Keyword:

tumor microenvironment, nanomedicine, Checkpoint inhibitor, spherical nucleic acids, gene expression/knockdown, and immunotherapy

Subject:

Nanotechnology, Oncology, and Immunology

Creator:

Chou, Liyushang

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/16/2023

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_884998 and http://dissertations.umi.com/northwestern:15965
Innate Immunity in Interleukin-33-Mediated Tumor Suppression: Competing Roles of Natural Killer Cells and Type 2 Innate Lymphoid Cells

Description:

Interleukin 33 (IL-33) is a complex inflammatory cytokine with diverse functions. In the context of cancer development, depending on the model, the implementation and dosage, and the immune cells involved, IL-33 can elicit dramatically different outcomes. Recent studies, including our own, have explored definitive contributions of the adaptive immunity in...

Keyword:

cancer immunology, natural killer cells, interleukin 33, Innate lymphoid cells, immunotherapy, and cd73

Subject:

Oncology and Immunology

Creator:

Long, Alan Wyndham

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_639294 and http://dissertations.umi.com/northwestern:14519

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Developing Immunotherapy Targeting Immune Suppression Using Spherical Nucleic Acids (SNAs)

Innate Immunity in Interleukin-33-Mediated Tumor Suppression: Competing Roles of Natural Killer Cells and Type 2 Innate Lymphoid Cells

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