Cancer remains a leading cause of death worldwide, necessitating continued study to explore and unravel its complex etiology. For example, there has been a shift of focus in cancer treatment from surgery and radiotherapy to targeted chemo- and immunotherapies as we gain more knowledge on the hallmarks of cancer (e.g.,...
Interleukin 33 (IL-33) is a complex inflammatory cytokine with diverse functions. In the context of cancer development, depending on the model, the implementation and dosage, and the immune cells involved, IL-33 can elicit dramatically different outcomes. Recent studies, including our own, have explored definitive contributions of the adaptive immunity in...