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Neurobiological Basis of in vivo Cortical Atrophy in Primary Progressive Aphasia Caused by Alzheimer’s Disease

Description:

The brain is known to shrink in normal aging or neurodegenerative disease and yet the neurobiological underpinnings of the cortical atrophy remain elusive. The structural changes that represent cortical atrophy can be measured during life using the reliable and quantitative method known as magnetic resonance imaging (MRI). Primary progressive aphasia...

Keyword:

primary progressive aphasia, neurons, cortical atrophy, activated microglia, and Alzheimer's disease

Subject:

Pathology, Medical imaging, and Neurosciences

Creator:

Ohm, Daniel Timothy

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_640035 and http://dissertations.umi.com/northwestern:14532
Functional Characterization of the Multi-domain Herpesvirus Essential Tegument Protein VP1/2: At the Core of Infectious Processes

Description:

The neurotropic alphaherpesviruses infect and spread trans-synaptically within the vertebrate nervous system. Recurrent diseases are often manifested at the periphery of the host organism but occasional dissemination of the virus to the brain results in fatal encephalitis. Interactions between viral and host cellular proteins are integral to the success of...

Keyword:

herpes, neurons, neuroinvasion, deubiquitinase, pseudorabies, and virus

Subject:

Neuroscience Institute Graduate Program

Creator:

Joy I-Hsuan Lee

Owner:

Scholarly Digital Publishing

Date Uploaded:

08/29/2018

Date Modified:

08/29/2018

Date Created:

2007-12-07

Resource Type:

Dissertation

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Neurobiological Basis of in vivo Cortical Atrophy in Primary Progressive Aphasia Caused by Alzheimer’s Disease

Functional Characterization of the Multi-domain Herpesvirus Essential Tegument Protein VP1/2: At the Core of Infectious Processes

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