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Tissue transglutaminase: A new method of facilitating hydrogel formation for cartilage regeneration and cartilage surface modification

Description:

Articular cartilage is a type of connective tissue that protects the underlying bone from the compressive forces of daily activities. When cartilage is damaged via a traumatic event, chondral defects are formed and require medical intervention. However, current treatments are of inconsistent efficacy and only benefit a subset of patients....

Keyword:

biomaterials, cartilage, transglutaminase, hydrogel, drug, and peptide

Subject:

Biomedical Engineering

Creator:

Marsha Elizabeth Ritter Jones

Owner:

Scholarly Digital Publishing

Date Uploaded:

09/12/2018

Date Modified:

09/12/2018

Date Created:

2008-05-06

Resource Type:

Dissertation
Studies in Natural Product Synthesis: Towards (1) Tambromycin and (2) the Solamin Stereoisomers

Description:

Total synthesis of natural products provides an avenue for investigation of complex chemical scaffolds, not only delivering access to biologically impactful molecules but also lending a deeper understanding of their inherent chemical reactivity. Expansion of reaction methodology, optimization of biological activity, and absolute structural confirmation can all be accomplished via...

Keyword:

allene, total synthesis, peptide, traceless Petasis reaction, natural product, and organic synthesis

Subject:

Organic chemistry and Chemistry

Creator:

Rote, Jennifer

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15164 and etdadmin_upload_750061

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Tissue transglutaminase: A new method of facilitating hydrogel formation for cartilage regeneration and cartilage surface modification

Studies in Natural Product Synthesis: Towards (1) Tambromycin and (2) the Solamin Stereoisomers

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