Northwestern University

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Filtering by: Keyword persistent inward currents Keyword neurodegeneration Keyword animal model

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Alterations of electrical properties in the adult motoneurons in the mSOD1 mouse model of Amyotrophic Lateral Sclerosis

Description:

In Amyotrophic Lateral Sclerosis (ALS), spinal motoneurons degenerate in the order of large motoneurons that innervate fast and fatigable muscle fibers to small motoneurons that innervate slow muscle fibers (Pun et al. 2006). This order of degeneration is peculiar in that it is in direct opposition to the normal order...

Keyword:

motoneurons, persistent inward currents, animal model, neurodegeneration, Amyotrophic lateral sclerosis, and electrophysiology

Subject:

Interdepartmental Neuroscience Program (NUIN)

Creator:

Seoan Huh

Owner:

Scholarly Digital Publishing

Date Uploaded:

04/16/2018

Date Modified:

04/16/2018

Date Created:

2017-01-01

Resource Type:

Dissertation