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Improving and engineering cell-free systems for glycoprotein production

Description:

The need to rapidly develop and produce life-saving vaccines and therapeutics is critical for overcoming pandemics in a global economy. Recent advances in automation and cell-free systems have opened new avenues for expediting optimization and production of biologic vaccines and therapeutics. A key consideration for the development of protein biologics...

Keyword:

biotechnology, bioproduction, glycosylation, vaccines, cell-free protein synthesis, and synthetic biology

Subject:

Chemical engineering

Creator:

Hershewe, Jasmine Marie

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_780613 and http://dissertations.umi.com/northwestern:15396
A Cell-Free Framework for Rapid Enzymatic Pathway Prototyping and Discovery

Description:

It is pertinent now more than ever that we find sustainable alternatives to produce chemicals. For decades, scientists and engineers have turned to biological systems to help meet societal needs in energy, medicine, materials, and moreespecially when chemical synthesis is untenable. Often, biologically-produced small molecules are insufficient for production at...

Keyword:

metabolic engineering, biotechnology, cell-free systems, biosynthetic pathway, synthetic biology, and enzymatic reactions

Subject:

Chemical and Biological Engineering

Creator:

Ashty Karim

Owner:

Scholarly Digital Publishing

Date Uploaded:

10/14/2019

Date Modified:

11/20/2019

Date Created:

2018-01-01

Resource Type:

Dissertation

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Improving and engineering cell-free systems for glycoprotein production

A Cell-Free Framework for Rapid Enzymatic Pathway Prototyping and Discovery

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