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Description:: The cause(s) of Aβ overproduction and accumulation in SAD are unknown; however, several lines of evidence indicate that impaired energy metabolism in the brain may be involved. Furthermore, the rate-limiting enzyme in Aβ production, BACE1, is elevated in SAD brains around amyloid plaques, indicating that BACE1 may also play a...
Keyword:: translation, energy metabolism, BACE1, amyloid, and Alzheimer's disease
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Tracy O'Connor
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/20/2018
Date Modified:: 09/20/2018
Date Created:: 2008-12-04
Resource Type:: Dissertation

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