Characterization is the musical creation of fictional characters, and it is particularly important for creating multi-dimensional, nuanced characters in opera. However, how do composers characterize roles if the opera does not feature a traditionally linear plot or story? Does opera need a narrative to create characterization? Some may view narrative...
The challenges of using inadequate online recruitment systems can be addressed with
machine learning and software engineering techniques. Bi-directional personalization
reinforcement learning-based architecture with active learning can get recruiters to recommend
qualified applicants and also enable applicants to receive personalized job recommendations.
This paper focuses on how machine learning...
Prostate cancer is the most common cause of cancer among men in the United States, and the second most common cause of cancer-related death, accounting for significant morbidity and mortality. This dissertation describes the genomic landscape of prostate cancer from multiple angles to identify mechanisms of disease heterogeneity amongst patients....
Current technologies capable of establishing bioresorbable orthopedic fixation devices and stents have broad utility for biomedical applications to improve constructive tissue remodeling. Recent studies and investigations on bioresorbable conductors, semiconductors, dielectrics, and polymer substrates offer a promising opportunity to propel the existing non-degradable bioelectronic devices to the promising bioresorbable electronics,...
The intersection of sound design and music scoring has been employed expressively in contemporary Mexican cinema to convey complex social commentary. This dissertation investigates how the Mexican films Vuelven, Sin Señas Particulares, and Sanctorum exploit the potentials of the soundtrack to create politicized aesthetic experiences. My research is in dialogue...
Body size is one of the most discernible ways in which animal species vary. The blue whale (Balaenoptera musculus), the largest animal on earth, can reach up to 30 m in length and weigh up to 200 tonnes. At the other extreme, a species of frog called Paedophryne amauensis is...
Cell-based therapies are an exciting frontier in medicine. This field is built on a simple premise—cells can be engineered to recognize and treat various human diseases. The paradigm of cell-based therapy uses biosensors to interrogate a cell’s environment and distinguish disease from health, intracellular signaling pathways and genetic circuitry to...
Electrochemical cell devices are increasingly being sought for energy conversion and storage applications due to their high efficiencies and their potential for operating free of greenhouse gas (GHG) emissions. Solid Acid Electrochemical Cells (SAECs), which most commonly employ CsH2PO4 (CDP) as the electrolyte component, are uniquely suited to meet the...
Migrant illegality gives way to irregular livelihoods in Spain and around the world. Studies on migrant illegality have generally focused on its political, legal and economic production and the social impact of a states specific biopolitics. While invaluably important, there remains the need to better understand the modes of life...
Plasminogen activator inhibitor-1 (PAI-1) is an essential mediator of senescence and a potential therapeutic target for preventing aging-related pathologies. Cellular Senescence is associated with organismal aging and related pathologies. In our study, we investigate the efficacies of PAI-1 inhibitors in both in vitro and in vivo models of homocysteine...
