Index Catalog // Arch : Northwestern University Institutional Repository

Description:: Breakthroughs in large-scale biological data collection have resulted in a wealth of -omics (genomics, metabolomics, etc.) datasets in the literature. However, the development of appropriate computational techniques for their analysis is lacking, yet crucial for fully extracting the rich information contained in these datasets. The work in this dissertation describes...
Keyword:: Biorecording, Data Storage, Cheminformatics, Metabolomics Annotation, Machine Learning, and TdT
Subject:: Bioengineering, Bioinformatics, and Biochemistry
Creator:: Strutz, Jonathan
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 09/22/2022
Date Created:: 2022-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_911481 and http://dissertations.umi.com/northwestern:16126

Description:: The Escherichia coli ribosome is a molecular machine capable of sequence-defined polymerization of -amino acids into proteins, a feat unmatched by any other current synthetic catalyst. It is complex in its structure, comprised of 3 RNA parts (the 5S, 16S, and 23S ribosomal RNAs) and 54 ribosomal proteins (r-proteins). Efforts...
Keyword:: Synthetic Biology, RNA Design, and Ribosome Engineering
Subject:: Bioengineering, Bioinformatics, and Chemical engineering
Creator:: Kim, Do Soon
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 10/06/2021
Date Created:: 2020-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_831423 and http://dissertations.umi.com/northwestern:15634

Description:: Platelets are circulating anucleate discs derived from megakaryocytes, and play major roles in hemostasis, inflammation, thrombosis, and vascular biology. Multi-phase culture systems for inducing in vitro platelet production from mature megakaryocytes have been explored to allow progenitor expansion, megakaryocyte maturation, and promotion of platelet formation and shedding. In this thesis,...
Keyword:: gaussian mixture models, stem cell differentiation, machine learning, and megakaryocyte
Subject:: Bioengineering, Bioinformatics, and Biology
Creator:: WU, JIA JIE
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/12/2020
Date Created:: 2019-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_640286 and http://dissertations.umi.com/northwestern:14541

LIBRARIES | ARCH