Index Catalog // Arch : Northwestern University Institutional Repository

Deciphering the Geometry of Primary Motor Cortical Manifolds: Observations from Naturalistic Movements and Implications for Intracortical Brain-Computer Interfaces

Description:: Each neuron in the primary motor cortex (M1) is like a musician in an orchestra, contributing to a larger harmony under the constraint of a “neural manifold”—a geometric score describing the correlated signals produced by the neural musicians that drive movement. Despite the widespread recognition of the importance of M1...
Keyword:: neural networks, neural manifolds, motor control, machine learning, and brain-computer interface
Subject:: Biomedical engineering and Neurosciences
Creator:: Altan, Ege
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 08/23/2023
Date Created:: 2023-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_1001502 and http://dissertations.umi.com/northwestern:16658

Towards modeling closed-loop sensorimotor integration in tactile sensing systems

Description:: The current view in neuroscience holds that the brain, together with its sensory and motor structures and the environment, form a closed-loop system – a sensorimotor loop – in which the brain receives information from the environment and converts it into a motor response while simultaneously making predictions about future...
Subject:: Biomedical engineering, Computer science, and Neurosciences
Creator:: Zweifel, Nadina Olivia
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 09/22/2022
Date Created:: 2022-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:16198 and etdadmin_upload_925059

Providing proprioceptive information through biomimetic multi-electrode stimulation patterns

Description:: Persons with spinal cord injuries can use state-of-the-art brain-computer interfaces to control robotic arms. Despite this high-tech solution, their movements are slow and imprecise, much like those made by individuals who have lost proprioception, the sense of body position and movement. Intracortical microstimulation (ICMS) used to reactivate neural circuits in...
Keyword:: proprioception, stimulation, prosthetic, and sensory
Subject:: Biomedical engineering and Neurosciences
Creator:: Sombeck, Joseph T
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 09/22/2022
Date Created:: 2022-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_917097 and http://dissertations.umi.com/northwestern:16157

Changes in Motor Unit Firing Patterns as a Function of Age, Muscle, and Following a Unilateral Brain Injury: Ionotropic and Metabotropic Effects

Description:: Coordinated movement relies on the precise and controlled activation of populations of motor units, which convert the commands of the nervous system into muscle forces. Motor unit firing patterns are often nonlinear and generated through the response to a combination of ionotropic excitatory and inhibitory commands, as well as metabotropic...
Keyword:: Motor Unit, Stroke, Persistent Inward Currents, Delta-F, Motoneuron, and Aging
Subject:: Biomedical engineering and Neurosciences
Creator:: Hassan, Altamash Shamsul
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 10/07/2021
Date Created:: 2021-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:15718 and etdadmin_upload_843639

Quantitative Probes to Explore Neural Mechanisms Driving Losses of Independent Joint and Limb Control Following an Early Unilateral Brain Injury

Description:: A one-time, unilateral injury to the developing brain can interrupt the typical process of development and result in motor impairments that evolve over the course of the whole life-span. The timing of injury relative to neural development has implications for the continued refinement of the nervous system and the descending...
Keyword:: mirror movement, cerebral palsy, corticospinal tract, reaching, pediatric hemiplegia, and flexion synergy
Subject:: Biomedical engineering and Neurosciences
Creator:: Hill, Nayo Marel
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 04/15/2021
Date Created:: 2021-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_792769 and http://dissertations.umi.com/northwestern:15452

Modeling Decision Making in Complex Naturalistic Environments

Description:: Decisions in naturalistic environments usually feature delayed and uncertain outcomes that can only be reached after a sequence of actions are performed. For example, canonical stalking and pursuit strategies used by terrestrial predators often involve stages of concealment, pauses where the predator remains motionless, and high speed chase sequences. The...
Keyword:: Ecology, Evolution, Decision Making, and Computational Neuroscience
Subject:: Ecology, Biomedical engineering, and Neurosciences
Creator:: Mugan, Ugurcan
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/01/2021
Date Created:: 2020-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_769384 and http://dissertations.umi.com/northwestern:15318

Sensory Substitution in the Presence of Vision: Providing Joint Speed Feedback to Improve Myoelectric Prosthesis Control and Adaptation

Description:: Maneuvering your limbs requires both accurate commands for how to move, and accurate feedback of their true movements. Conventional prosthetic arms currently lack this sense of proprioceptive feedback, which can make daily tasks difficult without close visual monitoring. Although studies have successfully provided artificial proprioceptive feedback to improve control, this...
Keyword:: motor adaptation, sensory feedback, and myoelectric prosthesis
Subject:: Biomedical engineering and Neurosciences
Creator:: Earley, Eric Joseph
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 04/28/2020
Date Created:: 2019-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_713001 and http://dissertations.umi.com/northwestern:14963

Design Rules to Control Mechanical Properties in 3D Hydrogels for Optimal Neuron Growth

Description:: Neurons are sensitive to the mechanical properties of their environment and show better growth, survival and differentiation when they are cultured in soft environments with mechanical properties similar to those of the brain compared to other tissues. Within the central nervous system (CNS), there is also a range of mechanical...
Keyword:: Hydrogels, Peptide amphiphiles, Mechanical properties, aza-glycine, Neurons, and Supramolecular
Subject:: Chemistry, Biomedical engineering, and Neurosciences
Creator:: Godbe, Jacqueline M
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 04/28/2020
Date Created:: 2020-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:15006 and etdadmin_upload_719165

The Contribution of Whole-Limb Kinematics to Proprioceptive Representations in the Central Nervous System

Description:: We have a remarkable ability to perform complex, coordinated movements without much conscious effort. In addition to the computations required to generate commands for muscles, a key aspect of coordinated motor control is incorporating sensory feedback about the movement. One of the most important feedback routes is through proprioception, the...
Keyword:: musculoskeletal model, somatosensory cortex, reaching, motion tracking, monkey, and cat hindlimb
Subject:: Biomedical engineering and Neurosciences
Creator:: Chowdhury, Raeed Hasan
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/12/2020
Date Created:: 2019-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:14692 and etdadmin_upload_666011

Deciding under duress: motor decisions of larval zebrafish under attack

Description:: We perform many movements every day without much deliberation. However, moving can be seen as a form of decision-making since one of many possible movements must be selected and executed. The decision-making processes that underlie movements are influenced by various factors, including sensory perception, energetics, time, perceived rates of failure...
Keyword:: hind brain, reticulospinal, decision, escape, spinal cord, and looming
Subject:: Biomedical engineering, Neurosciences, and Biomechanics
Creator:: Bhattacharyya, Kiran
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/12/2020
Date Created:: 2019-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_653282 and http://dissertations.umi.com/northwestern:14560

The Role of Motor Planning in Reaching and the Impact of Stroke

Description:: Motor planning is fundamental to the performance of everyday reaching movements. The influence of planning is not limited to voluntary movements but extends to involuntary movements initiated in response to sensory stimuli, such as postural perturbations applied to the arm. Stroke alters voluntary reaching and the involuntary response to perturbations,...
Keyword:: Startle, Stroke, Motor Planning, and Reaching
Subject:: Biomedical engineering and Neurosciences
Creator:: Heckman, Rosalind Lauren
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/12/2020
Date Created:: 2018-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_625731 and http://dissertations.umi.com/northwestern:14442

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Deciphering the Geometry of Primary Motor Cortical Manifolds: Observations from Naturalistic Movements and Implications for Intracortical Brain-Computer Interfaces

Towards modeling closed-loop sensorimotor integration in tactile sensing systems

Providing proprioceptive information through biomimetic multi-electrode stimulation patterns

Changes in Motor Unit Firing Patterns as a Function of Age, Muscle, and Following a Unilateral Brain Injury: Ionotropic and Metabotropic Effects

Quantitative Probes to Explore Neural Mechanisms Driving Losses of Independent Joint and Limb Control Following an Early Unilateral Brain Injury

Modeling Decision Making in Complex Naturalistic Environments

Sensory Substitution in the Presence of Vision: Providing Joint Speed Feedback to Improve Myoelectric Prosthesis Control and Adaptation

Design Rules to Control Mechanical Properties in 3D Hydrogels for Optimal Neuron Growth

The Contribution of Whole-Limb Kinematics to Proprioceptive Representations in the Central Nervous System

Deciding under duress: motor decisions of larval zebrafish under attack

The Role of Motor Planning in Reaching and the Impact of Stroke

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