Index Catalog // Arch : Northwestern University Institutional Repository

1. Integrative Modeling of Contaminant Accumulation in Highly Altered Aquatic Ecosystems

Description:: The world's aquatic food webs are currently in crisis due to the cumulative, interacting effects of anthropogenic pressures including non-indigenous species invasions, chemical contamination, overfishing, habitat disruption and global climate change. Efforts to restore or protect the integrity and sustainability of these systems are limited by a lack of knowledge...
Keyword:: Invasive Species, Global Change, Bioaccumulation, and Food Web
Subject:: Chemical and Biological Engineering
Creator:: Carla Aparecida Ng
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/08/2018
Date Modified:: 09/08/2018
Date Created:: 2008-05-07
Resource Type:: Dissertation

2. New Insights from Network Theory and Analysis: From the Mechanics of Granular Materials to the Robustness of Cellular Metabolism

Description:: Granular matter and living cells represent two extremes of what have come to be regarded as complex systems - systems characterized by a richness in global behavior that is not easily deduced from the interactions of their individual parts, even when those interactions are simple and well understood. On the...
Keyword:: Engineering
Subject:: Chemical and Biological Engineering
Creator:: Ashley Smart
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/30/2018
Date Modified:: 08/30/2018
Date Created:: 2007-12-07
Resource Type:: Dissertation

3. Nicotinamide Enhances Primary Human Megakaryocytic Differentiation from Hematopoietic Stem Cells: Phenotypic Characterization and Mechanism of Action

Description:: Megakaryocytic cells (Mks) are derived from hematopoietic stem cells (HSCs) and give rise to platelets. Ex vivo culture of HSCs under conditions that promote Mk differentiation has been proposed as a method for producing Mks and platelets for cell therapies. Mk maturation involves the development of polyploid cells via endomitosis,...
Keyword:: Chemical and Biological Engineering
Subject:: Chemical and Biological Engineering
Creator:: Lisa Marie Giammona
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/06/2018
Date Modified:: 08/06/2018
Date Created:: 2007-07-23
Resource Type:: Dissertation

4. Genome-Scale Transcriptional Analysis of Megakaryocytic Cell Cultures Reveals Insights into Lineage-Specific Differentiation

Description:: Little is known about the transcriptional events underlying megakaryocytic (Mk) differentiation from hematopoietic stem cells. We sought to identify genes and pathways not previously associated with megakaryopoiesis and to evaluate the CHRF-288-11 (CHRF) megakaryoblastic cell line as a model system for investigating megakaryopoiesis. Using DNA microarrays, Q-RT-PCR, and protein-level assays,...
Keyword:: p53, microarray, differentiation, apoptosis, polyploidization, and megakaryocyte
Subject:: Chemical and Biological Engineering
Creator:: Peter Gebhard Fuhrken
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/06/2018
Date Modified:: 08/06/2018
Date Created:: 2007-07-12
Resource Type:: Dissertation

5. Discerning the Therapeutic Potential of Peptoid-Based Mimics of Bioactive Proteins

Description:: Nature has been evolving innovative solutions to complex design challenges for billions of years, the success of which is evidenced by the myriad of life-sustaining systems that operate with unparalleled simplicity, efficiency, and durability. Biomimetic researchers derive inspiration from principles underlying natural phenomena to solve design challenges. This work is...
Keyword:: peptoids, in vivo, antimicrobial peptides, lung surfactant, and biomimetics
Subject:: Chemical and Biological Engineering
Creator:: Ann Marie Czyzewski
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/20/2018
Date Modified:: 09/20/2018
Date Created:: 2008-12-01
Resource Type:: Dissertation

6. Effects of Nanoscale Confinement and Interfaces on the Structural Relaxation of Amorphous Polymers Monitored at the Molecular Scale by Fluorescence and Dielectric Spectroscopy

Description:: Over the past decade and a half, there has been considerable interest in the effect confinement and interfaces have on the properties of glass forming materials. With the emergence of nanotechnology, some glass formers, in particular polymeric glass formers, will be used at increasingly smaller length scales. An understanding of...
Keyword:: Fluorescence Spectroscopy, Confinement Effects, Polymers, Glass Transition, Physical Aging, and Dielectric Spectroscopy
Subject:: Chemical and Biological Engineering
Creator:: Rodney Dewayne Priestley
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/12/2018
Date Modified:: 09/12/2018
Date Created:: 2008-05-01
Resource Type:: Dissertation

7. Polymer Matrices and Dynamic Coatings for Ultra-fast DNA Sequencing Separations by Electrophoresis in Glass Microfluidic Chips

Description:: Separation of DNA molecules by electrophoresis through entangled polymer solutions continues to be an important tool for genetic analysis, especially Sanger-based DNA sequencing. Separations of DNA on microfluidic devices are much more efficient than in capillary electrophoresis (CE) systems, such that the implementation of DNA sequencing onto microchips promises to...
Keyword:: Chemical Engineering
Subject:: Chemical and Biological Engineering
Creator:: Christopher Paul Fredlake
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/31/2018
Date Modified:: 08/31/2018
Date Created:: 2008-05-01
Resource Type:: Dissertation

8. Biobased and Biodegradable Polymer Blends and Nanocomposites with Superior Dispersion and Physical Properties Created Using Solid-State Shear Pulverization

Description:: Growing concerns associated with global warming and the depletion of oil reserves have motivated significant research in support of sustainable polymers systems. In this thesis, biobased and biodegradable polymer blends and nanocomposites were created using a novel processing method, solid-state shear pulverization (SSSP). This process utilizes a modified twin-screw extruder...
Keyword:: Polymers
Subject:: Chemical and Biological Engineering
Creator:: Amanda Marie Flores
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/08/2018
Date Modified:: 10/08/2018
Date Created:: 2008-10-14
Resource Type:: Dissertation

9. Peptide Biomimicry: Structure-Activity Relationships of Peptoid Analogues of Lung Surfactant Protein C

Description:: The adoption of surfactant replacement therapy (SRT) for the treatment of neonatal respiratory distress syndrome (nRDS) is one of the main contributors to the dramatic decline in infant mortality rates observed in the 1980s. Despite the significant efficacy of animal-derived surfactant preparations, there are still some concerns associated with their...
Keyword:: Engineering
Subject:: Chemical and Biological Engineering
Creator:: Nathan James Brown
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/08/2018
Date Modified:: 10/08/2018
Date Created:: 2008-12-05
Resource Type:: Dissertation

10. METABOLIC ENGINEERING OF CLOSTRIDIUM ACETOBUTYLICUM FOR ENHANCED BUTANOL PRODUCTION AND SELECTIVITY

Description:: To increase the butanol titers and selectivity in Clostridium acetobutylicum we replaced the promoter of the alcohol/aldehyde dehydrogenase (aad) gene with the phosphotranbutyrylase (ptb) promoter and combined this with CoAT downregulation to minimize acetone production. This led to early production of high alcohol (butanol plus ethanol) titers and overall solvent...
Keyword:: metabolic engineering and Clostridium acetobutylicum
Subject:: Chemical and Biological Engineering
Creator:: William Sillers
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/01/2018
Date Modified:: 10/01/2018
Date Created:: 2008-12-04
Resource Type:: Dissertation

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1. Integrative Modeling of Contaminant Accumulation in Highly Altered Aquatic Ecosystems

2. New Insights from Network Theory and Analysis: From the Mechanics of Granular Materials to the Robustness of Cellular Metabolism

3. Nicotinamide Enhances Primary Human Megakaryocytic Differentiation from Hematopoietic Stem Cells: Phenotypic Characterization and Mechanism of Action

4. Genome-Scale Transcriptional Analysis of Megakaryocytic Cell Cultures Reveals Insights into Lineage-Specific Differentiation

5. Discerning the Therapeutic Potential of Peptoid-Based Mimics of Bioactive Proteins

6. Effects of Nanoscale Confinement and Interfaces on the Structural Relaxation of Amorphous Polymers Monitored at the Molecular Scale by Fluorescence and Dielectric Spectroscopy

7. Polymer Matrices and Dynamic Coatings for Ultra-fast DNA Sequencing Separations by Electrophoresis in Glass Microfluidic Chips

8. Biobased and Biodegradable Polymer Blends and Nanocomposites with Superior Dispersion and Physical Properties Created Using Solid-State Shear Pulverization

9. Peptide Biomimicry: Structure-Activity Relationships of Peptoid Analogues of Lung Surfactant Protein C

10. METABOLIC ENGINEERING OF CLOSTRIDIUM ACETOBUTYLICUM FOR ENHANCED BUTANOL PRODUCTION AND SELECTIVITY

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1. Integrative Modeling of Contaminant Accumulation in Highly Altered Aquatic Ecosystems

2. New Insights from Network Theory and Analysis: From the Mechanics of Granular Materials to the Robustness of Cellular Metabolism

3. Nicotinamide Enhances Primary Human Megakaryocytic Differentiation from Hematopoietic Stem Cells: Phenotypic Characterization and Mechanism of Action

4. Genome-Scale Transcriptional Analysis of Megakaryocytic Cell Cultures Reveals Insights into Lineage-Specific Differentiation

5. Discerning the Therapeutic Potential of Peptoid-Based Mimics of Bioactive Proteins

6. Effects of Nanoscale Confinement and Interfaces on the Structural Relaxation of Amorphous Polymers Monitored at the Molecular Scale by Fluorescence and Dielectric Spectroscopy

7. Polymer Matrices and Dynamic Coatings for Ultra-fast DNA Sequencing Separations by Electrophoresis in Glass Microfluidic Chips

8. Biobased and Biodegradable Polymer Blends and Nanocomposites with Superior Dispersion and Physical Properties Created Using Solid-State Shear Pulverization

9. Peptide Biomimicry: Structure-Activity Relationships of Peptoid Analogues of Lung Surfactant Protein C

10. METABOLIC ENGINEERING OF CLOSTRIDIUM ACETOBUTYLICUM FOR ENHANCED BUTANOL PRODUCTION AND SELECTIVITY