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The Role of TACC3 in Regulating Microtubule Dynamics During Herpesvirus Infections

Description:

The microtubule (MT) network and associated regulatory proteins play a critical role during viral infection from facilitating viral particle transport towards the nucleus upon entry to later mediating virion assembly and egress. Many of the precise mechanisms by which viruses commandeer the host MT network to propagate infection remain poorly...

Keyword:

TACC3, virus, microtubules, and +TIP

Subject:

Virology, Microbiology, and Cellular biology

Creator:

Furey, Colleen Patricia

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/02/2022

Date Created:

2021-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_856328 and http://dissertations.umi.com/northwestern:15823
A cellular examination of TLR3 antiviral function in human iPSC-derived CNS and sensory neurons

Description:

Herpes simplex encephalitis (HSE) is a rare and severely debilitating life-threatening disease caused by herpes simplex virus type 1 (HSV-1) infection of the human central nervous system (CNS). The severe and often fatal outcomes of HSE contrast starkly with the more frequent and largely benign consequences of herpes labialis. Whole...

Keyword:

Herpes, PNS, Toll like receptors, TLR3, CNS, and Innate immunity

Subject:

Virology, Microbiology, and Immunology

Creator:

Ewaleifoh, Osefame

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14704 and etdadmin_upload_667366

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The Role of TACC3 in Regulating Microtubule Dynamics During Herpesvirus Infections

A cellular examination of TLR3 antiviral function in human iPSC-derived CNS and sensory neurons

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