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The TRIP8b-HCN Interaction as a Therapeutic Target

Description:

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are expressed in the heart and central nervous system where they regulate membrane excitability. Recently, inhibiting HCN channels in the hippocampus has been identified as a possible therapeutic intervention for the treatment of Major Depressive Disorder (MDD). However, based on the high expression level of...

Keyword:

HCN, OPC, Oligodendrocyte, TRIP8b, and Depression

Subject:

Neuroscience, Biochemistry, and Developmental Biology

Creator:

Kyle Andrew Lyman

Owner:

Scholarly Digital Publishing

Date Uploaded:

06/17/2019

Date Modified:

06/17/2019

Date Created:

2016-01-01

Resource Type:

Dissertation

Alternate Identifier:

https://doi.org/10.21985/N2W781