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- Description:
- Proper partitioning of mitochondria and mtDNA is critical for cellular health. Investigations into mitochondrial inheritance, specifically how mtDNA inheritance is coupled with the inheritance mitochondrial compartment, are still in the early stages. We use budding yeast as a model polarized cell system to study a mitochondrial Myo2-adaptor protein, Mmr1, in...
- Keyword:
- mitochondria, mitochondrial tethering, mtDNA, Mmr1, and mitochondrial inheritance
- Subject:
- Molecular biology, Biochemistry, and Cellular biology
- Creator:
- Chen, WeiTing
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_763646 and http://dissertations.umi.com/northwestern:15245
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- Description:
- The study and design of machines that are able to analyze the auditory scene and organize sound into parts that are perceptually meaningful to humans is referred to as machine hearing. Such machines are expected to distinguish between different sound categories (e.g., speech, music, background noise), focus on a sound...
- Keyword:
- Audio Source Separation, Common Fate, Machine Hearing, Audio Signal Processing, Audio Classification, and Audio Representation
- Subject:
- Electrical engineering and Computer science
- Creator:
- Pishdadian, Fatemeh
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_780859 and http://dissertations.umi.com/northwestern:15404
-
- Description:
- Intelligence in humans is largely characterized by the ability to encode information into compressible representations to facilitate efficient communication for collaboration and learning. The goal of this thesis is to enable robots to both learn and act on compressible representations in real-time. I show how active exploration with respect to...
- Keyword:
- Information Communication, Human-Robot Interaction, and Robot Learning
- Subject:
- Robotics
- Creator:
- Prabhakar, Ahalya
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15341 and etdadmin_upload_772609
-
- Description:
- While optimization has received much attention in the machine learning community, most of them consider unconstrained supervised learning models such as neural networks and support vector machine. In this dissertation, we introduce a new class of optimization problems called scale invariant problems that include interesting unsupervised learning models such as...
- Keyword:
- Power Iteration, PCA, Optimization, Machine Learning, Scale Invariance, and KL-NMF
- Subject:
- Applied mathematics and Operations research
- Creator:
- Kim, Cheolmin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15139 and etdadmin_upload_744178
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- Description:
- This thesis focuses on applications of recurrent neural networks (RNNs) for three aspects of sequential classification. In the first chapter, a novel method to generate synthetic minority data generation to improve imbalanced classification is discussed. Generative Adversarial Networks (GANs) have been used in many different applications to generate realistic synthetic...
- Keyword:
- Explainability, Recurrent Neural Networks, and Machine Learning
- Subject:
- Applied mathematics
- Creator:
- Ger, Stephanie Kwang-Yu
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15394 and etdadmin_upload_780385
-
- Description:
- Two major areas of research in the field of manufacturing are miniaturization and 3D printing. The trend towards miniaturization stems from the desire and need for additional functionality and improved performance for products with ever-smaller footprints. Miniaturization opens manufacturing to new applications such as tissue engineering and surface texturing. Meanwhile,...
- Keyword:
- micro-manufacturing, micro-additive manufacturing, near-field electrospinning, residual charges, and electrohydrodynamics
- Subject:
- Mechanical engineering
- Creator:
- Martinez Prieto, Nicolas
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15128 and etdadmin_upload_743961
-
- Description:
- Social factors are a major contributor to deaths in the US. The literature suggests that socioeconomic status and other social and environmental factors influence an individual’s mortality. These factors encompass six domains that comprise factors such as poverty, unemployment, poor access to healthy food, limited access to health care, limited...
- Keyword:
- Social Determinants of Health, Hospitalization, Mortality, Health Insurance, and Emergency Department
- Subject:
- Health sciences, Health care management, and Public health
- Creator:
- Wang, Andrew C
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15384 and etdadmin_upload_780174
-
- Description:
- Social media and online forums provide spaces where people can gather beyond restrictions of geographic proximity. For some individuals with mental illness, these spaces are vital; providing outlets and communities where a multitude of experiences are accepted and understood, rather than judged against normative, often ableist standards. For nearly three...
- Keyword:
- Social Computing, Human-Computer Interaction, Digital Ethnography, Mental Illness, Eating Disorders, and Anti-Oppressive Care
- Subject:
- Information science, Computer science, and Communication
- Creator:
- Feuston, Jessica
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_768803 and http://dissertations.umi.com/northwestern:15315
-
- Description:
- Granular mixing has received less attention than fluid mixing due to the unique properties of granular materials and the complexity of their flow behaviors. Unlike fluid flows, where a continuum perspective accurately captures flow behavior, neither a continuum nor a discrete perspective by itself can describe the global behaviors of...
- Keyword:
- Granular materials, Mixing and segregation, and tumbler flow
- Subject:
- Chemical engineering
- Creator:
- Yu, Mengqi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_780245 and http://dissertations.umi.com/northwestern:15389
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- Description:
- Bacteria often coordinate virulence factors to fine-tune the host response during infection. These coordinated events can include toxins counteracting or amplifying effects of another toxin or though regulating the stability of virulence factors to remove their function once it is no longer needed. Multifunctional autoprocessing repeats-in toxin (MARTX) toxins are...
- Keyword:
- Toxin, MAPK, IL-8, Vibrio vulnificus, MARTX, and Vibrio cholera
- Subject:
- Microbiology, Molecular biology, and Immunology
- Creator:
- Woida, Patrick James
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15369 and etdadmin_upload_778406