This paper investigates the use of self-assembled monolayers
(SAMs) to optimize the localized surface plasmon resonance (LSPR)
biosensor for disease detection. Various experiments were done
with 1-(9-mercaptononyl)-3,6,9-trioxaundecan-11-ol (TDT) and
heptaoxatricosanoic acid (HSA), a new SAM; these included a solvent
study to determine refractive index sensitivity and nonspecific binding
and specific...
Under the correct conditions, aluminum can be anodized in an electrochemical
cell to produce hexagonally ordered arrays of nanoscale
pores. This study examines how adding the chemicals methanol and
acetic acid to a typical anodization solution alters pore-growth patterns
across the surface oxide layer. The existence of the unique pore-growth...
Thermoelectric materials, which convert heat energy to electrical
energy, may become increasingly important in the world’s energy
situation. Through the inclusion of nanoscale features embedded within
a thermoelectric bulk material, it has been shown that a corresponding
decrease in lattice thermal conductivity results in an enhanced
thermoelectric figure of merit,...
Alzheimer’s disease (AD) is one of the most common forms of dementia,
with no current definitive premortem diagnosis. Amyloid beta-peptide
derived diffusible ligands, known as ADDLs, have become a key link in
the AD specificity for memory loss and are a potential biomarker for AD.
In order to develop an...
Neurons are difficult to manipulate experimentally. Most transfection
reagents used for gene silencing are neurotoxic, and the postmitotic
state of neurons prevents the effective use of viral vectors. This study
demonstrated the delivery of antisense DNA against target genes by
gold nanoparticle oligonucleotide complexes (GNOs) in primary cultures
of rat...
Magnetic nanostructures (MNS) have become the subject of intense
interest due to their superparamagnetic properties and consequently
their potential uses in medical diagnostics and therapeutics. In this
study, monodisperse magnetite MNSs were synthesized via thermal
decomposition of iron(III) acetylacetonate and transferred to aqueous
solution using 11-aminoundecanoic acid as the surfactant....
The emergence of lightwave communication and computing, and applications in nanophotonics require an understanding of complex electromagnetic wave phenomena in linear and nonlinear materials having frequency-dependent and intensity-dependent polarizations. Both the complexity of the underlying physics and the problems required for modern engineering applications necessitate understanding the vector-nature of the...
The combined trends of decreasing application size and increasing requirements for energy efficiency have driven a need for improved understanding and better predictive tools for thin film lubricated systems. Research on such systems is complicated by the involvement of both larger scale phenomena such as fluid flow, material deformation, and...
Although recent research has provided some evidence to suggest that positive mood is associated with increased interpersonal trust, our understanding of the underlying explanation for why this occurs is far from complete. The current project presents the results from 4 experiments which were designed to understand both when, and why,...
My work in Comparative Literary Studies and French explores the link between the Mande oral tradition and its literature to reveal the presence and absence of the griots' words and their portrayal in the novel. Authors Amadou Hampaté Bâ (L'Étrange Destin de Wangrin); Massa Makan Diabaté (L'Assemblée de Djinns); D.T....