Two-year colleges are a critical site for the expansion of educational opportunity in the United States. They enroll nearly half of all postsecondary students and are a gateway to higher education for low-income, non-traditional, racial and ethnic minority, and first-generation college students. Degree completion rates in the two-year sector are...
Most women diagnosed with epithelial ovarian carcinoma (EOC) initially present with metastases, but little is known about the regulation of ovarian tumor cell dissemination by the tumor microenvironment. Because ovarian cancer cell dissemination is mostly limited to the peritoneal cavity and often results in the accumulation of malignant ascites, the...
Arsenic trioxide (As<sub>2</sub>0<sub>3</sub>) is an arsenic-derivative that exhibits potent growth inhibitory effects against malignant cells. The remarkable antitumor effects of As<sub>2</sub>0<sub>3</sub> in vitro and in vivo have prompted the development of various clinical trials that established its activity in acute promyelocytic leukemia (APL). As<sub>2</sub>0<sub>3</sub> is part of the standard treatment...
The work presented here represents a series of research projects that are unified in their goal: to use volume holographic gratings to enhance traditional signal processing applications in ways that would otherwise not be possible. To this end, we have completed work that can be classified into four different projects....
Fundamental investigations on the origins of friction at the nanoscale were carried out using both theoretical and experimental approaches. A model was developed that analytically solves for friction by the motion of dislocations at atomically flat crystalline interfaces. It combines known concepts from dislocation drag, grain boundary theory, and contact...
Solid oxide fuel cells (SOFCs), renowned for their high electrical generation efficiency with low pollutant production, are promising for reducing global energy and environmental concerns. However, there are major barriers for SOFC commercialization. A primary challenge is reducing the capital cost of SOFC power plants to levels that can compete...
><p><em>Vibrio cholerae</em>, the causative agent of the severe diarrheal disease cholera, secretes several "accessory" toxins including RTX toxin, which causes cross-linking of the actin cytoskeleton. The rtx locus of <em>V. cholerae</em> is located adjacent to the integrated CTX? prophage. The RTX toxin itself is encoded by the <em>rtxA</em> gene found...
In response to construction activities and loads from permanent structures, soil generally is subjected to a variety of loading modes varying both in time and location. It also has been increasingly appreciated that the strains around well-designed foundations, excavations and tunnels are mostly small, with soil responses at this strain...
Contemporary pattern of relationship between European Union and Africa-Caribbean and
Pacific countries reflects more than two centuries of unequal exchange. Unequal exchange
between the North and the South denotes the falling terms of trade for underdeveloped countries,
while correspondingly increasing the terms of trade for the developed countries. It has...
Perhaps better suited for the mosh pit than the orchestra pit, David Lang’s 1991 tour-de-force for solo bass clarinet, Press Release, is a minimalist marvel. Comprised of seven “groove sections” that evolve in seemingly unpredictable ways, Lang cleverly employs monophony to tell a robust story of motivic and harmonic development....