This book discusses how cities that have developed through the successive stages of capitalism should transform themselves when adapting to the conditions of the contemporary global age. Since modern times, the capitalist economy has largely defined society, politics, and environment—this has casued the collapse of communities, the crisis of democracy,...
The intersection of sound design and music scoring has been employed expressively in contemporary Mexican cinema to convey complex social commentary. This dissertation investigates how the Mexican films Vuelven, Sin Señas Particulares, and Sanctorum exploit the potentials of the soundtrack to create politicized aesthetic experiences. My research is in dialogue...
Sentence comprehension requires both syntactic prediction and working memory processes. Evidence suggests that both are impaired in agrammatic aphasia, and can independently contribute to comprehension breakdowns, but the relationship between them, especially during real-time sentence comprehension remains unclear. Two EEG studies investigated on-line processing of sentences with non-local long-distance dependencies...
The commitment of resources to coaching almost always occurs in interaction with other district-wide efforts to improve instruction. Given this probable situation, it’s concerning that the field lacks the ability to provide guidance regarding how coaches might reasonably be integrated within overall plans for the coordination and improvement of instruction....
Tissue-infiltrating neutrophils (polymorphonuclear neutrophils [PMNs]) are a prominent feature of inflammatory bowel disease (IBD) and colorectal cancer (CRC), where these immune cells can promote cytotoxicity or exacerbate disease outcomes. We recently showed that in acute colon injury, PMNs can increase DNA double-strand break (DSB) burden and promote genomic instability via...
In the United States, allergic disease affects approximately 60 million people and impacts more people every year. While prevalence of allergic disease has steadily increased, there has concurrently been an increase in rates of metabolic syndrome—characterized by increased abdominal girth, decreased sensitivity to insulin, and higher levels of circulating blood...
Facts are not enough! The more recent wave of science communication practices have been advocating for the death of the deficit model of science communication. This model notes that by possessing sufficient information, individuals will change their attitude and behavior to align with scientific facts. However, recent research has shown...
This paper discusses the role of the Secondary Rainbow Synthesizer in Catherine Lamb’s composition Prisma Interius IX. This instrument is a MIDI keyboard that controls a computer program consisting of a bank of resonant band-pass filters, which are tuned to specific frequencies and can be opened or closed to varying...
Biomedical imaging is an essential part of medicine that enables the non-invasive observation of biological phenomena. This, in turn, allows for more accurate and earlier diagnoses, monitoring of therapies, and even fundamental research into biological processes. Molecular imaging, a fast-growing subdiscipline of biomedical imaging, seeks to image biochemical processes at...
Otoacoustic emissions are currently used for various clinical purposes; however, stimulus frequency otoacoustic emissions (SFOAEs) evoked using a single one are not utilized clinically due to uncertainties regarding their generation mechanism, their spatial source(s) in the cochlea, and their susceptibility to various cochlear insults, particularly in humans. Over the years,...
Emergent phenomena are phenomena that only arise from the bulk collective, not from individual pieces of that collective. The design of materials which host emergent phenomena can be achieved by controlling the interactions between constituent atoms, ions, or electronic spins in a material, and include materials such as permanent magnets...
Rocky exoplanets are indicated to be common in the galaxy. Future instruments including the {\it James Webb Space Telescope} (JWST), high resolution ground-based spectrographs, and direct imaging missions for under consideration by the 2020 Decadal Survey on Astronomy and Astrophysics are poised to unlock the atmospheres of habitable zone planets...
In the adult hippocampus of many mammalian species, populations of newborn dentate granule cells (DGCs) are continuously generated and undergo subsequent activity-dependent neuronal maturation and incorporation into the preexisting hippocampal circuitry. Increasing evidence has demonstrated that these young adult-born DGCs (abDGCs) participate in numerous cognitive and affective processes such as...
RNA viruses cause a wide range of diseases that range from mild respiratory illness to fatal hemorrhagic fevers. To combat these pathogens, most cells in the human body scan the cell for viruses and activate a potent cell-intrinsic immune response by producing interferon (IFN), a cytokine that amplifies the innate...
Part I: Evaluating the relationship between Crosslink Kinetics and Thermodynamics with the hydrogel mechanics. The past two decades have witnessed a surge of applications built upon dynamic covalent chemistry (DCC), both attributed to the scope of developed reactions as well as their modularity.1-3 These reactions have comparable strengths to their...
This dissertation is a culmination of work spanning several modes of travel, multiple datasets, and different contexts. Because the proliferation of new mobility services disrupted the transportation ecosystem, I aim to understand travel behavior and investigate how new and traditional modes intermingle. I focus my attention on Mobility-on-Demand which encompasses...
Models of recursive preferences are commonly associated with a preference for early resolution of uncertainty, often regarded as an important economic channel in applications. This dissertation provides a different understanding of recursive preferences based on attitudes toward correlation, and in particular aversion to intertemporally correlated risks. Part 1 provides a...
Even though a number of techniques have been developed for motion generation and perception, few of them focus on the computational efficiency and theoretical guarantees at the same time. Typically, improved guarantees come with increased complexity, making theoretically guaranteed methods challenging use in real-time applications. Thus, existing methods usually have...
Thermoelectric devices utilize semiconducting n-type and p-type thermoelectric materials to convert heat into electricity. Despite their promise for deep space power generation or waste heat recovery, most high-performing thermoelectric materials reported in literature are absent in practical applications - partially due to inconsistent synthesis and poor mechanical performance. This work...
All animals purposefully navigate feature-rich environments: while exploring, in search of vital resources of food and water, finding mates, and patrolling and marking habitats. During these complex behaviors, continuous analogue input information from peripheral sensory organs guides discrete and digital sequential motor output; accordingly, each action is informed, modulated, or...
In this dissertation, I assert that a contradictory aesthetic has remained and been reborn in the U.S. daytime soap opera through time and technology; I call this the “everyday implausible.” Using textual analysis and archival research, I follow this genre from its beginnings on radio, through its move to television...
Asymmetric relationships between creators and consumers in peer-produced knowledge repositories produce inequitable knowledge representation--or knowledge gaps. These gaps result in unequal access to information, and downstream technologies that leverage peer-produced data perpetuate these inequities. Effective knowledge gap identification represents a necessary first step towards equitable knowledge representation. However, while prior...
Eukaryotic genomes are organized into chromatin, which acts to regulate access to the organism’s genetic material. A large and diverse class of proteins, known as chromatin modifiers and remodelers, are responsible for regulating the composition and structure of chromatin by monitoring nucleosomes. Chromatin remodelers are involved in multiple cellular processes,...
Urban Air Taxi (UAT) is the use case of passenger-carrying Urban Air Mobility (UAM) at its mature state, and it offers a ubiquitous on-demand (or nearly on-demand) per-seat service that moves passengers in urban or suburban areas using groundbreaking aircraft. However, the absence of a dominant electric vertical take-off and...
The first chapter of this dissertation looks at strategic complementarities among investors inpooled investment vehicles where fund managers and investors have different objectives. Could
lessening strategic complementarities among the investors of a fund make investing in the fund
less appealing? Exploiting the 2014 Reform of the money market mutual fund...
Dendritic microstructures form during the solidification of a variety of metal parts, from traditionally cast engine blocks to 3D-printed specialty tooling. These dendrites can evolve through growth, coarsening, fragmentation, and the formation of a Columnar-to-Equiaxed Transition (CET), which all can greatly affect material properties. However, the basic science behind these...
Market growth is an important goal for consumer businesses, often leading to lower marginal cost, higher operational efficiency, and larger assortment size - all of which help achieve dominance over competition. Yet, retailers and manufacturers alike should carefully manage their supply chains to sustain growth in customer base and extract...
Scalable processing of well-defined interfaces is key not only for wider application of two-dimensional (2D) materials in technology but also for improved fundamental understanding. Atomic layer deposition has useful characteristics, especially self-limited growth at low temperatures, that make it well suited for the production of uniform interfaces. Related processes, such...
Over 10 billion tons of concrete are produced for the construction industry every year, making concrete the second most used substance on Earth, only surpassed by water. With such high importance as a building material, there is significant need for the ability to accurately model concrete behavior. As a quasi-brittle...
Sensorimotor integration is a general term to describe how task-specific motor output is generated from the selective and rapid processing of sensory and motor information. The rodent vibrissal (whisker) system is an important model for the study of sensorimotor integration and active tactile sensing. This research uses the rodent vibrissal...
RAS is one of the most frequently mutated oncogenes in cancer with ~30% of all human tumors harboring a mutation in either HRAS, NRAS, or KRAS isoforms. Despite countless efforts for the development of small molecule inhibitors for RAS, it remains an elusive target in the clinic. Here I demonstrate...
With the rapid growth of demand for data center services, the energy and water use of data centers has become a critical concern in the contexts of energy use, climate change, and freshwater conservation. Therefore, understanding, quantifying, and optimizing the use of energy and water resources in data centers has...
The rise and racial gap in maternal mortality and morbidity in the US growing public health crisis. The US maternal mortality rate is double that of peer countries such as the UK and Canada. Even more striking, Black women are 243% more likely to die from childbirth-related causes. According to...
Wearable-based human activity recognition is well-studied in the machine learning and pervasive computing community. A large corpus of studies focused on using wearable sensors to recognize health-related behaviors that involve high periodicity in the sensed signal, such as sitting, walking, and running. Other activities that occur less frequently throughout the...
Automated driving has become a very popular topic in the recent years and is becoming more and more of a reality. In this new trend, High Definition (HD) maps play an important role in many ways that will provide a safer and more efficient driving experience, especially in terms of...
Infection with the novel coronavirus, SARS-CoV-2, results in pneumonia and other respiratory symptoms as well as pathologies at diverse anatomical sites. An outstanding question is whether these diverse pathologies are due to replication of the virus in these anatomical compartments and how and when the virus reaches those sites. To...
Modern data sets are increasingly vast, not only in the number of samples, but also in the number of measurements, or features, that they contain. This high-dimensionality poses a unique set of problems for data analysis due to a set of phenomena known as ``the curse of dimensionality.'' This thesis...
We consider general utility models and information structures of the agents and illustrate when economic conclusions for designing simple mechanisms in classical settings extends for general environments. We show that whether economic conclusions can be generalized depends on the details of the generalizations. For example, in single-item auction, competition and...
In the wake of environmental catastrophe, active intervention is needed to heal trauma, resist erasure, and navigate changing communities. Focusing on New Orleans after the federal levee failures following Hurricane Katrina, this dissertation looks across a diverse mix of case studies to theorize how communities utilize performance to navigate mass...
Prostate cancer is the most common cause of cancer among men in the United States, and the second most common cause of cancer-related death, accounting for significant morbidity and mortality. This dissertation describes the genomic landscape of prostate cancer from multiple angles to identify mechanisms of disease heterogeneity amongst patients....
Bioelectronic devices at the biotic/abiotic interface face a number of key challenges that include device degradation when exposed to biological fluid, their elicited immune response due to mechanical mismatch, and poor signal transduction. Organic electronic materials and their devices, such as organic electrochemical transistors (OECTs) address these shortcomings. They can...
This dissertation explores the experience of violence and precarity among Central American youth as they travel through Mexico to the United States. Based on a multi-sited ethnographic study conducted across Mexico from 2015 to 2019, I illustrate how the journey of these youth migrants is, in its basic expression, an...
Does race matter globally, beyond national and regional contexts? If yes, then how exactly? I argue that race matters globally and develop an account for understanding that significance. I call the account “global racial capitalism.” In chapter 1, I offer background to motivate and defend the thesis that race matters...
Numerous insights into the sensorimotor systems that guide the control of voice have been garnered by observing how the system responds to manipulations of its auditory feedback. However, current approaches may be limited in the exploration of more complex parameters of volitional and adaptive voice control due to their limited...
Triplet excited state chemistry has enabled a range of important organic transformations by accessing reaction pathways inaccessible to photoredox chemistry. Such photoreactions are triggered by triplet photosensitizers, which absorb visible-light photons and transfer the energy to the substrate or to a co-catalyst through triplet-triplet energy transfer (TT EnT). The most...
The airway epithelial cells (AECs) lining the conducting passageways of the lung secrete a variety of immunomodulatory factors. One interesting pair of molecules produces by AECs is IL-6 and prostaglandin E2 (PGE2). PGE2 limits lung inflammation and promotes bronchodilation. By contrast, IL-6 drives intense airway inflammation, remodeling, and fibrosis. The...
Enzyme substrate promiscuity has significant implications for metabolic engineering. The ability to predict the space of possible enzymatic side reactions is crucial for elucidating underground metabolic networks in microorganisms, as well as harnessing novel biosynthetic capabilities of enzymes to produce desired chemicals. Reaction rule-based cheminformatics platforms have been implemented to...
Mixing by cutting-and-shuffling (like that for a deck of cards or a Rubik's cube) is a paradigm that has not been studied in detail even though it can be applied in a variety of situations including the mixing of granular materials. Mathematically, cutting- and-shuffling is described by piecewise isometries (PWIs),...
With the ever-increasing demand for more complex functionalities and miniaturization of photonic devices, the design of such devices requires a whole new different approach, deviating from classical photonic design approaches. Conventionally, the design of a typical photonic device starts with a prior knowledge, intuition, and practical experience of specific behavior...
SAMDI-MS, which stands for self-assembled monolayers (SAMs) for matrix-assisted laser desorption ionization (MALDI) mass spectrometry (MS), is a powerful tool that has enabled the development of novel high-throughput screening and experimentation methods for decades. SAMDI-MS works by immobilizing analytes to functionalized SAMs prior to MS analysis and is capable of...
Between the 1880s and the 1980s, typography mutated from an entirely manual, craft-based practice to a comprehensively mechanized, then a fully digitized one. With the arrival of Apple’s Macintosh computer in 1984, the graphic design profession found itself in the midst of a deep transformation of its tools, techniques, and...
While the scholarship on policing and surveillance suggests that police departments have and use a wide array of sophisticated tools, the literature has largely focused on only a handful of the largest departments. Moreover, these studies tend to be qualitative, so it is difficult to pinpoint what factors might be...
The cerebellar cortical system is an extensively studied circuit which is critical for motor learning. While multiple monoamines, such as norepinephrine and serotonin, modulate cerebellar cortical output, the mechanistic details of dopaminergic signaling in the cerebellum remain poorly understood. Additionally, neuronal cell types residing within the cerebellum remain relatively under-characterized....
This dissertation studies three aspects of healthcare market regulation.
Chapter 1 studies the optimal design of quality scores for health insurance plans. Regulators often generate quality scores to help consumers with limited information about product quality, as in schooling, healthcare, and financial markets. When designing scores, regulators must not only...
This dissertation explores how a nonprofit network orchestrator went through revolutionary change in response to the COVID-19 pandemic. Throughout data collection, the nonprofit sector grappled with uncertainties about the funding landscape (Batsell, 2020), how to deliver programming when in-person interactions were impossible (Warren, 2020), substantial job losses (Newhouse 2021a; Newhouse...
This dissertation studies interactions between a non-Bayesian decision maker (DM) and a sophisticated information provider who wants to influence the DM. In the essay ``Strategic Justifications," an auditor receives a justification from a self-interested expert who wants to convince the auditor that she acted in good faith for her clients....
Finite Element Method (FEM) is a common simulation method in Computer Aided Engineering (CAE) or studying natural phenomenon by numerically solving Partial Differential Equations (PDEs). Programmable solvers for generic physics and geometry are thus highly desirable. However, the classical solvers are mostly complex systems in terms of both their mathematical...
In most markets, consumers of goods and services have vastly more options available to them than they will consider closely. At the point of making a decision, consumers are choosing between only a small subset (i.e., a consideration set) of all possible alternatives. The preceding process that forms these consideration...
Individual responses are an important determinant of public policy effectiveness. Development policies often try to remove barriers that limit the ability to make the preferred choices, hoping that this will lead to prosperity at the individual and aggregate levels. However, removing some, but not all, barriers can lead to undesirable...
With the increasing demand for customized products, rapid prototyping, and small-batch production, incremental sheet forming (ISF) is gaining ever-growing attention. The potential of ISF to produce parts without the use of geometry-specific dies has revolutionized the sheet forming processes. Despite its promising characteristics, ISF thus far has not been extensively...
“(Being a) Feminist (is a) Struggle: Intersectional Feminist Politics in the Era of the Women’s March” argues that contemporary feminist politics are characterized by debates and contestations concerning the political demands of intersectionality. Contemporary feminist theory and politics are particularly and peculiarly preoccupied with making these judgements about the political...
This paper studies the joint importance of dissemination and the structure of firms’ information networks in the pricing of value relevant financial information. I first document that disruptions to the dissemination of information on Twitter.com cause the market to react less to earnings news. Using ten staggered Twitter outages, which...
A prominent cause of premature ovarian insufficiency (POI) is gonadotoxic cancer therapies, which deplete the ovarian reserve of follicles, oocytes, and hormone-producing cells. Current fertility preservation methods include the removal and cryopreservation of ovarian tissue prior to gonadotoxic treatment. This cryopreserved tissue can be transplanted back and has been found...
Engineering responses of soft materials at hierarchical time and length scales is of great interest to both fundamental science and technological applications. In recent years, the hybridization between emerging soft condense matters and conventional hard condense matters keeps enriching the materials library of humankind and opens another largely-uncharted venue for...
Having an Experience: Media Franchises, Events, & Participatory Culture explores, like its title suggests, what we mean when we talk about “having an experience” in today’s media culture. Traveling to an expanded network of sites where media fans are actively called to go out and “have an experience” in the...
Reproduction requires a complex orchestration of processes from the formation of the reproductive system through the successful development of the fetus, and nutrients are necessary to fuel these processes during many aspects of reproduction. Zinc is an essential metal that is fundamental in gamete maturation, gonadogenesis, and fertilization. Disruption in...
I set up a disagreement model where traders not only have different interpretations of a public signal that conveys information of a stock, but are also uncertain about the information quality of others' interpretations. The model along with traders being ambiguity-averse predicts a positive relation between investor disagreement (ID) and...
Chapter 1 proposes and tests a model where a country aligns with a foreign power to obtain its support and reduce its geopolitical risks, which also depend on the country's exposure to the other foreign powers. We show that the country's alignment with a given foreign power is increasing in...
This dissertation consists of three chapters that each study the interaction between government policy and real estate markets. All three chapters are connected by a broad interest in renters, landlords, and rental markets. Chapter 1 investigates the relationship between place-based policies and real estate and rental markets empirically by studying...
The NLRP3 inflammasome is a multi-protein complex that drives sterile and pathogen-dependent inflammation. Activation of the NLRP3 inflammasome occurs in two steps: priming and activation. Priming occurs in response to an inflammatory stimulus, such as LPS. LPS-primed macrophages are subsequently activated by a second stimuli, most of which require K+...
Art has been tied to scientific and technological advancements throughout history, providing methods and mediums for communication, expression, and exploration. Art is a dialogic domain that evolves with the technological advances in society–incorporating technology and computational tools to create new genres of art. We live in an increasingly computational and...
The last two decades have seen tremendous growth in the development of techniquesfor molecular state control. The goal of achieving complete control over the quantum states
of a molecule is motivated by a plethora of applications ranging from many-body physics
to precise tests of fundamental physics. The level of control...
In this dissertation, we study the birational geometry of log pairs over the field of complex numbers, with an emphasis on the positivity properties of log pairs and their applications. First, we study the nonvanishing conjecture in the minimal model program. We prove the nonvanishing conjecture for uniruled log canonical...
X-rays have become a staple in the investigation of the natural world. The high penetration and short wavelength of X rays means extended samples can be imaged at high resolution. With the increasing brightness of synchrotron light sources as well as the development of commercial sources the continued development and...
This dissertation centers gay and lesbian activists, their lawyers, and public interest litigation organizations in a genealogical understanding of the evolution of human rights law in the LGBTIQ+ issue space. I ask why sexual minorities turned to the courts in pursuit of the decriminalization of homosexual sex. Empirically, I examine...
This thesis examines the role of the media in stock markets and the role of transparency in investment decisions. In the first two chapters, I investigate how the contrasting trends in media coverage and earnings guidance have affected stock price informativeness over the past two decades. I develop a model...
The goal of this dissertation is to develop models, algorithms, and interaction protocols to improve the efficacy and quality of Human-Autonomy Interaction (HAI) in the domain of assistive robotics. In this domain, the most common control paradigm is that of manual teleoperation using control interfaces such as joysticks, switch-based head...
Individuals with psychotic disorders experience profound challenges in maintaining a coherent sense of self and identity over time. Although disturbances in the basic, momentary sense of self are core features of psychotic experiences, less is known about psychosis’s impact on the autobiographical self, the experience of being a coherent and...
This dissertation consists of three chapters on contract theory. In Chapter 1, ``Agency in Hierarchies: Middle Managers and Performance Evaluations'', I study the optimal joint design of incentives and performance rating scales in a principal-manager-worker hierarchy. The principal wants to motivate the manager and the worker to exert unobservable effort....
Regardless of where refugees are hosted, they require political knowledge of rights, restrictions, responsibilities, and the governance actors and processes who decide and uphold these. This knowledge enables refugees to comply with national laws, benefit from rights and protections, avoid rights-based exploitations and harms, and pursue life with dignity in...
This dissertation consists of three chapters on empirical industrial organization. The first chapter explores how a seller uses a public reserve price to signal her private info about the object’s value to the bidder. The second chapter studies how a behavioral consumer preference called “price reference effect” could overturn the...
Background: The way in which one perceives their visual world (i.e., bottom-up visual perception) and what one pays attention to in their surroundings (i.e., top-down attention), are critical to uncovering underlying thoughts and cognitions, and impact how one operates in the social world. Individuals with autism spectrum disorder (ASD), a...
ABSTRACT This dissertation moves work on school discipline into the digital era by filling a gap in the literature which has largely ignored how data from digital student ecosystems are mined and processed by school authority. My dissertation interrogates the role youth of youth online behavior in school discipline decision-making....
This dissertation is the culmination of a four-year project on local governments and local economic activity during the Great Depression in the United States (1929 - 1937). Chapter 1 investigates how U.S. municipal governments coped during the Depression and studies whether debt-induced financial constraints affected local public good provision. Local...
Since the invitation of ARPANet in 1969, network protocols and communication systems have continued to emerge. Especially in the past decade, the prosperity of mobile internet and cloud computing has resulted in a large number of network protocols and communication systems, which have become critical infrastructure for our society. Availability...
Yugoslav wartime television news often conformed to the demands of the political regimes. Informed by this knowledge, scholars have argued that TV as a medium incited and legitimized the wars by fostering ethnonationalist ideologies. Using archival and textual analysis, this project examines how television reacted to the political constraints imposed...
The past decade has seen the rapid progress of deep learning, which becomes a game-changing technique in different data-intensive domains, with the availability of large scale data, cost-effective computing hardware and more advanced learning theory and algorithms. Despite of the rapid progress of deep learning methods in daily-life applications, such...
From energy to materials, hydrocarbon chemistry drives our world. Stemming from the petrochemical industry, our understanding of CxHy combinations has allowed society to flourish, and hydrocarbons will likely remain valuable species in our future even as we transition to greener carbon and hydrogen sources. Currently, one of the most efficient...
This thesis consists of three chapters: two are empirical studies of policy design in small-business lending markets, while the final is a large-scale retrospective of retail mergers. Chapter 1 examines moral hazard in loan guarantee programs. To address credit constraints in small-business lending markets, policymakers frequently rely on loan guarantees,...
This thesis describes an exploratory project to develop a highly non-traditional approach to devise novel test methods for characterizing the properties of materials that are essential to the design of sustainable and resilient infrastructure, particularly naturally occurring materials such as soils and rocks. The central idea is that the material...
Failed continental rifts provide unique opportunities to study aspects of plate tectonic evolution frozen in time. North America contains three major failed rifts: The Midcontinent Rift (MCR), Southern Oklahoma Aulacogen (SOA), and the Reelfoot Rift (RR). To understand why some rifts fail and why others might succeed to seafloor spreading,...
Additive manufacturing (AM), also known as three-dimensional (3D) printing, has received considerable interests in recent years. It enables fabrication of complex, customizable parts that would otherwise be too expensive or impossible for traditional manufacturing methods. 3D printing encompasses a wide variety of processes, including photopolymerization, material extrusion, selective laser sintering,...
Myoelectric pattern recognition-based upper limb prostheses measure electromyographic (EMG) signals from the residual limb and learn to identify muscle activity patterns that correspond to intended gestures. To train an accurate pattern recognition controller, it is essential that the training signals typify signals measured in real-world scenarios. When these conditions are...
Within scholarship on mid-century Hollywood musicals, celebrity, glamour, and spectacle are commonly included in the conversation about the films themselves. Yet, what happened when these films – which privilege visuality – were adapted into purely aural forms, has not been as deeply analyzed. In this project, I track the cross-media...
Emotional processing deficits are characteristic of psychotic disorders such as schizophrenia. However, impairments as such are not well understood prior to the onset of psychosis among individuals at clinical high-risk (CHR). This dissertation draws from prominent theories of emotion in schizophrenia and seeks to investigate the experience and expression of...
Sequential change-point detection for time series enables us to sequentially check the hypothesisthat the model still holds as more and more data are observed. It’s widely used in data monitoring
in practice. In this work, we propose two models: Binomial AR(1) model and Generalized
Beta AR(p) model, for modeling binomial...
Using the context of the oil and natural gas boom of North Dakota and Montana brought on by advances in hydraulic fracturing technology, this dissertation studies how changing economic conditions affect basic social well-being in a rural setting. Using methods of causal inference, specifically difference-in-differences regressions and comparative interrupted time-series...
Cancer is a top leading cause of deaths worldwide, among which pancreatic cancer and liver cancer are top leading cause of cancer-related deaths. Despite recent developments in cancer treatment, pancreatic and liver cancers still have a high mortality and low life expectancy, especially when diagnosed at advanced stages. Earlier cancer...
With growing system complexity and closer cyber-physical interaction, there are stronger needs for cyber-physical systems to adapt to the dynamic environment and improve their runtime performance. However, especially for safety-critical systems, the ability of such adaptation and improvement is often restricted by multiple factors, such as limited resources, stringent timing...