The purpose of this study was to select an
alloy with a low driving force for nucleation
for a more in-depth study of the nucleation
of γ’-precipitates. To do this, three Ni-Cr-Al
alloys were chosen close to the solvus line
of a Ni-Cr-Al phase diagram, ensuring low
supersaturation and therefore...
Second harmonic generation (SHG),
a nonlinear optical tool, was used to
characterize DNA bound through a
chemical linker to the flat surface of a
hemispherical lens. Contact angle
measurements were used to guarantee
that the chemical linker did not hydrolyze
under experimental conditions. SHG
experiments followed the effects of salt...
Nitrogen (N) deposition can alter belowground microbial communities, especially ectomycorrhizal (ECM) fungi, resulting in a reduced ability of associated trees to access organic nutrients. This study tested whether N addition decreases ECM species richness and shifts ECM species composition across spatial scales in a subtropical slash pine (Pinus elliottii) plantation...
Part 1. The complex folded structures associated with RNA allow for specific protein-RNA interactions and also create binding sites for small molecules. Developing organic molecules that can bind RNA with high affinity and specificity is a challenge that must be overcome for RNA to be considered a viable drug target....
In this dissertation we analyze, using standard formal imperfect competition models from the literature, two central public policy issues in the deregulated wholesale electricity markets. The first issue is the regulatory rules around generator ownership of transmission companies or transmission rights in general. The second issue we look into is...
In mammalian development, cell specification and organogenesis are achieved by the regulated expression and repression of specific subsets of genes. The anterior pituitary gland, comprised of five cell types that arise from a common precursor, is an excellent model system for understanding these developmental processes. Examination of factors regulating transcription...
Autoxidation is a primary route by which lubricants in working conditions undergo degradation. Degraded lubricants, if not replaced periodically, contribute to increased wear and product failure. Experimental studies of lubricant degradation have yielded useful results but have left important questions unanswered. While many computational studies of degradation have been carried...
The goal of this dissertation was to examine the influence of motivational incentives on visual spatial attention in patients with probable Alzheimer's Disease (PRAD), patients with mild cognitive impairment (MCI) and healthy age-matched control subjects (EC). Specifically, I compared the ability of monetary incentives to influence behavioral and neural performance...
There is increasing evidence that links chronic activation of glial cells and the subsequent self-propagating cycle of neuroinflammation to the neurodegenerative progression of Alzheimer's disease (AD). Nevertheless, attempts to identify currently approved drugs capable of safely attenuating the neuroinflammatory processes in AD have proven disappointing to date, and the development...
This final report contains information on years 6-7-8 (2004-2007) of TEA-21 funded projects designated A487, W420, and A212. The report was submitted by Morris E. Fine and Semyon Vaynman in 2007.
Performance monitoring of deep excavations typically includes slope inclinometers, optical surveying of soil deformation, tiltmeters and strain gages. Current monitoring data collection and processing requires time consuming site visits and manual data reduction by project engineers. Development of robotic and remote access geotechnical instrumentation conceptually allows processed data to be...
The textbook proceeds with an introduction to theory and concept building, moves to an explanation of causal inference (how do we 'know' whether something is causal?), and then provides a quick introduction to data and hypothesis testing. Following that, each chapter is devoted to a particular research method used within...
Understanding how spin waves propagate through ferromagnets is an important component of a wider international effort to create spintronic devices. In this thesis, we develop a propagating spin wave spectroscopy to make a variety of measurements on thin films of Yttrium Iron Garnet (YIG), a material known for having long...
B_s mixing studies provide a precision test of Charge-Parity violation in the Standard Model. A measurement of deltaMs constrains elements of the CKM quark rotation matrix, providing a probe of Standard Model Charge-Parity violation.
This thesis describes a study of B_s mixing in the semileptonic decay B_s -> D_s mu...
During interactions with our environment we must incorporate information about the mechanical properties of obstacles into our motor actions. Fundamental to these behaviors is the ability to simultaneously control movements of the hand while regulating the interaction forces that arise from contact with the environment. Although the neural control of...
In recent years, moral and political philosophers have begun to focus upon the impact of pluralism on conceptions of civic obligation, legitimacy, and justice. According to the political liberalism of John Rawls, citizens should justify their political views in terms of values that are neutral among divergent worldviews; they should...
This project examines the relationship between graphic design and public life in an effort to understand how graphic design functions as a mode of communication, how visual images present interpretive problems for communication scholarship, and how the increasing presence of visual images in public space inform and are informed by...
In the age of what George W. Bush has called a global democratic revolution, the freedom to consume an ever-expanding variety of images and goods in the global marketplace is often equated with the conditions of democratic freedom. With just such rhetorical elisions in mind, this dissertation examines the discursive...
Experimental and numerical studies of lasing in multiple light scattering media with gain are presented in this thesis. Depending on the dielectric constant spatial distribution is random or periodic, two different kinds of lasers are discussed: the random laser and the photonic crystal laser. This thesis, therefore, is divided into...
Spectral elements are p-type element which can provide better accuracy
and faster convergence. However, applications of these elements make
conformation to discontinuities in the function or its derivative
difficult. The eXtended Finite Element Method (XFEM) recently
developed at Northwestern University can easily treat the arbitrarily
aligned discontinuities, i.e. independent of...
Two-year colleges are a critical site for the expansion of educational opportunity in the United States. They enroll nearly half of all postsecondary students and are a gateway to higher education for low-income, non-traditional, racial and ethnic minority, and first-generation college students. Degree completion rates in the two-year sector are...
Most women diagnosed with epithelial ovarian carcinoma (EOC) initially present with metastases, but little is known about the regulation of ovarian tumor cell dissemination by the tumor microenvironment. Because ovarian cancer cell dissemination is mostly limited to the peritoneal cavity and often results in the accumulation of malignant ascites, the...
Arsenic trioxide (As<sub>2</sub>0<sub>3</sub>) is an arsenic-derivative that exhibits potent growth inhibitory effects against malignant cells. The remarkable antitumor effects of As<sub>2</sub>0<sub>3</sub> in vitro and in vivo have prompted the development of various clinical trials that established its activity in acute promyelocytic leukemia (APL). As<sub>2</sub>0<sub>3</sub> is part of the standard treatment...
The work presented here represents a series of research projects that are unified in their goal: to use volume holographic gratings to enhance traditional signal processing applications in ways that would otherwise not be possible. To this end, we have completed work that can be classified into four different projects....
Fundamental investigations on the origins of friction at the nanoscale were carried out using both theoretical and experimental approaches. A model was developed that analytically solves for friction by the motion of dislocations at atomically flat crystalline interfaces. It combines known concepts from dislocation drag, grain boundary theory, and contact...
Solid oxide fuel cells (SOFCs), renowned for their high electrical generation efficiency with low pollutant production, are promising for reducing global energy and environmental concerns. However, there are major barriers for SOFC commercialization. A primary challenge is reducing the capital cost of SOFC power plants to levels that can compete...
><p><em>Vibrio cholerae</em>, the causative agent of the severe diarrheal disease cholera, secretes several "accessory" toxins including RTX toxin, which causes cross-linking of the actin cytoskeleton. The rtx locus of <em>V. cholerae</em> is located adjacent to the integrated CTX? prophage. The RTX toxin itself is encoded by the <em>rtxA</em> gene found...
In response to construction activities and loads from permanent structures, soil generally is subjected to a variety of loading modes varying both in time and location. It also has been increasingly appreciated that the strains around well-designed foundations, excavations and tunnels are mostly small, with soil responses at this strain...
Contemporary pattern of relationship between European Union and Africa-Caribbean and
Pacific countries reflects more than two centuries of unequal exchange. Unequal exchange
between the North and the South denotes the falling terms of trade for underdeveloped countries,
while correspondingly increasing the terms of trade for the developed countries. It has...
This thesis contains four essays on the organization (both internal and external) of health care in the US. The first essay examines a mechanism through which individual workers acquire (or maintain) competence, namely that of experience. Specifically, I analyze whether cardiac surgeons who perform more procedures experience an improvement in...
Perhaps better suited for the mosh pit than the orchestra pit, David Lang’s 1991 tour-de-force for solo bass clarinet, Press Release, is a minimalist marvel. Comprised of seven “groove sections” that evolve in seemingly unpredictable ways, Lang cleverly employs monophony to tell a robust story of motivic and harmonic development....
This dissertation examines the construction and regulation of over-the-counter derivatives markets before and after the 2007-2009 global financial crisis. It addresses two questions: How did the market for derivatives traded outside traditional exchanges grow so large and crisis-prone with so little public regulation? And, why, given derivatives’ contribution to the...
This paper describes the technology and methods deployed in the continuous autonomous remote monitoring of cracks in interior and exterior walls of a residence near a limestone quarry. The object is to quantitatively compare crack response to blast-induced ground motion to that induced by diurnal temperature changes, weather fronts, and...
Teasing is commonplace in our social interactions (Kowalski, 2007). Due to its paradoxical nature it can be employed to produce both positive and negative outcomes (Keltner et al., 1998) however, the ambiguity and subjectivity in teasing can make it susceptible to misinterpretation (Kowalski, 2000; 2007; Kruger et al., 2006). The...
Musical theater is a discipline that, by its very nature, engages several disciplines, specifically music, visual art, theater, and dance. The elementary classroom is a viable setting for the study of the arts in an interdisciplinary manner, yet the number of studies examining interdisciplinary instruction with regard to elementary music...
On 6 February 2007, President Bush announced that the United States would
create a new military command for Africa, to be known as Africa Command or Africom.
Throughout the Cold War and for more than a decade afterwards, the U.S. did not have a
military command for Africa; instead, U.S....
In this dissertation, we explore modeling and solution methods for intermodal drayage operations. This research is motivated by the need to provide operational choices in drayage operations to increase efficiency; however, as shown in our work, the introduction of this flexibility in modeling and solution methods is challenging.
Intermodal freight...
After 9/11 there was a shift in the rhetoric surrounding counter-terrorism. Suddenly, the language of risk, security and prevention was being utilized to justify a new set of global financial regulations headed up by international organizations such as the United Nations, The Financial Action Task Force, and the IMF/World Bank....
Background: Evidence supporting a bidirectional relationship between depression and recurrent cardiovascular disease (CVD) appears strong, but there remains a need to better characterize the role of depression in CVD risk and cardiovascular health (CVH) promotion, especially in the context of comorbid risk factors such as cigarette smoking. In the present...
Every music theorist has their own personal reasons for engaging in the craft of theorizing about music. Many discover that there is something special about a theoretic disposition which differs from other sorts of interactions with music. It is often this special something that draws musicians into the discipline: specifically,...
Every music theorist has their own personal reasons for engaging in the craft of theorizing about music. Many discover that there is something special about a theoretic disposition which differs from other sorts of interactions with music. It is often this special something that draws musicians into the discipline: specifically,...
Leakage currents limit the operation of high performance type II InAs/GaSb superlattice photodiode technology. Surface leakage current becomes a dominant, limiting factor to the ideal performance of a photodiode, especially at the scale of a focal plane array pixel (< 25 µm), and must be addressed. A reduction of the...
The addition of nanoparticles into polymer materials has been observed to dramatically change the mechanical, thermal, electrical, and diffusion properties of the host polymers, promising a novel class of polymer matrix composite materials with superior properties and added functionalities that are ideal candidates in many applications, including aerospace, automobile, medical...
Two subjects are the focus of this dissertation: Au/TiO2 catalyst used for oxidation of CO at low temperature and siloxane nanocages, a novel material (~2nm) recently developed in our group
While bulk gold is chemically inert, gold supported as nanoparticles is remarkably active for the oxidation of carbon monoxide at...
An efficient unified incremental high-level and physical-level synthesis algorithm was presented in Chapter 2, which enable the tight integration between high-level and physical-level design. Chapter 3 presented a temperature-aware high-level synthesis algorithm built upon the framework of Chapter 2. Temperature variations and hot spots account for reliability issue and require...
The contents of this dissertation are divided into two sections: (1) the preparation and characterization of quaternary rare-earth chalcogenides and oxychalcogenides and (2) the localized surface plasmon resonance (LSPR) spectroscopy of metallic nanoparticles fabricated by nanosphere lithography (NSL).
Single crystals of CsTmCoS3, CsYbCoS3, CsHoCoSe3, CsYbCoSe3, and CsYbZnSe3 have been prepared...
This dissertation describes the use of alkanethiols and polymers for the development of lithographic affinity and resist array templates that can be utilized for directing the assembly of biological molecules, for building up multilayered polyelectrolyte thin films, and for fabricating metal solid-state nanostructures. The first two chapters of the work...
In this thesis we discuss the issue of solving stochastic optimization problems using sampling methods. Numerical results have shown that using variance reduction techniques from statistics can result in significant improvements over Monte Carlo sampling in terms of the number of samples needed for convergence of the optimal objective value...
This thesis examines the effects of micro-alloying additions to Al-Sc alloys on the microstructure, coarsening resistance and creep properties. The overarching goal of this research is to develop castable, creep-resistant aluminum alloys which can be used at temperatures in excess of 300?C. Successful high-temperature application of aluminum based alloys offers...
This dissertation argues that theatre was a vital element of postcolonial culture in Ireland in the years 1919-1932, the period in which the Irish nation emerged from revolutionary war to become a stable postcolonial state. Although critics have bemoaned the rising dominance of conservative, anti-modernist playwriting and production in Ireland's...