Localized Surface Plasmon Resonance Nanobiosensors for the Detection of a Prostate Cancer Biomarker

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Silver nanoparticles exhibit distinctive optical properties. When exposed to electromagnetic radiation, a noble metal nanoparticle demonstrates the unique optical property of localized surface plasmon resonance (LSPR). LSPR is measured through an extinction spectrum, the sum of absorption and Rayleigh scattering, which results when the collective oscillation of electrons is resonant with the incident photon frequency. The specific binding of a prostate cancer biomarker, such as prostate specific antigen (PSA), to a PSA specific antibody can be monitored by using LSPR. This study contributes to the work toward detection and quantification of extremely low levels of PSA.

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  • 07/19/2018
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