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  1. The Role of Early Growth Response Transcription Factors in Hematopoietic Development

    Description: The orderly process of hematopoietic differentiation is governed in large part by the coordinated transcription of specific genes. Deregulation of normal differentiation processes can lead to disease states including immunodeficiency, autoimmune disease, and leukemia. This research focuses on the family of transcription factors known as the early growth response (Egr)...
    Keyword: thymocyte, Egr, macrophage, and transcription
    Subject: Integrated Graduate Program in the Life Sciences
    Creator: John Carter
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/12/2018
    Date Modified: 09/12/2018
    Date Created: 2008-05-09
    Rights: In Copyright
    Resource Type: Dissertation
  2. The Role of E6 Domains and Promoter Regulation in the HPV 31 Life Cycle

    Description: Tonia René Holverson The HPV genome contains a bipartite promoter system that regulates the expression of early and late gene transcripts. The early proteins include the replication proteins E1 and E2, the oncoproteins E6 and E7, and the late functioning proteins E4 and E5. The late proteins include the capsid...
    Keyword: promoter, E6, transcription, and HPV
    Subject: Integrated Graduate Program in the Life Sciences
    Creator: Tonia Rene' Holverson
    Owner: Scholarly Digital Publishing
    Date Uploaded: 08/31/2018
    Date Modified: 08/31/2018
    Date Created: 2008-04-23
    Rights: In Copyright
    Resource Type: Dissertation
  3. Computational design of Small Transcription Activating RNAs (STARs) for versatile and dynamic gene regulation

    Description: A longstanding goal of synthetic biology has been the programmable control of cellular functions. Central to this is the creation of versatile regulatory toolsets that allow for programmable control of gene expression. Of the many regulatory molecules available, RNA regulators offer the intriguing possibility of de novo design – allowing...
    Keyword: RNA, synthetic biology, RNA engineering, gene regulation, and transcription
    Subject: Synthetic Biology and RNA engineering
    Creator: James Chappell, Alexandra Westbrook, Matthew Verosloff, and Julius B. Lucks
    Owner: Julius Beau Lucks
    Publisher: MacMillan Publishers
    Language: English
    Date Uploaded: 08/03/2017
    Date Modified: 08/16/2017
    Date Created: 2017-08-03
    Rights: Attribution 3.0 United States
    Resource Type: Dataset
    Identifier: doi:10.21985/N28S9B