Limit your search
Search Constraints
Number of results to display per page
Search Results
-
- Description:
- This dissertation explores how the environment shapes energy expenditure and cardio-metabolic disease risk by investigating multiple timescales of adaptation to cold stress among the Yakut, an indigenous circumpolar population. This study pursues three main objectives. First, the adaptive and health significance of brown adipose tissue (BAT) is explored by examining...
- Keyword:
- Anthropology
- Subject:
- Anthropology
- Creator:
- Stephanie B Levy
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/09/2019
- Date Modified:
- 01/09/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- This project examines how early modern writers mobilize race as a vehicle for investigating far-reaching epistemological questions about the limits and parameters of human knowledge. While dominant trends in early modern race studies have focused on racial knowledges or particular identifications or formulations of human difference, I break new ground...
- Keyword:
- epistemology, history of science, race, literature and science, and colonialism
- Subject:
- English
- Creator:
- Meghan Daly Costa
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/09/2019
- Date Modified:
- 01/29/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Large projection neurons of the cerebellar nuclei (CbN cells), whose activity generates movement, are inhibited by Purkinje cells and excited by mossy fibers. The high convergence, firing rates, and strength of Purkinje inputs predict powerful suppression of CbN cell spiking, raising the question of what activity patterns favor excitation over...
- Keyword:
- deep cerebellar nuclei, cerebellum, dynamic clamp, Purkinje cell, rate coding, and temporal coding
- Subject:
- Interdepartmental Neuroscience Program (NUIN)
- Creator:
- Yeechan Wu
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/09/2019
- Date Modified:
- 01/09/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- The goal of science education is to prepare students to make decisions about the complicated socioscientific issues that are an inescapable part of modern life, from personal medical decisions to evaluating a political candidate's environmental platform. We cannot expect adults to maintain a deep conceptual understanding of the current state...
- Keyword:
- media literacy, epistemology, science journalism, science education, and assessment
- Subject:
- Learning Sciences
- Creator:
- Brandy Liane Evans Buckingham
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/09/2019
- Date Modified:
- 01/09/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Ions dissolved in solution are known to interact in remarkable ways with charged Langmuir monolayers. The organic monolayer can be used as a molecular template for ordered nucleation of inorganic crystals (biomineralization) and functional nanoparticles. However, the clear majority of experiments demonstrating these behaviors have been performed with divalent ions....
- Keyword:
- John Ketterson
- Subject:
- Physics and Astronomy
- Creator:
- Mitchell Miller
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/09/2019
- Date Modified:
- 01/09/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Humans possess the ability to infer and track mental states, which allows for successful interaction in the social world. The collection of processes and representations that makes this possible is referred to as a theory-of-mind (ToM). A large body of work has examined how these abilities develop from infancy to...
- Keyword:
- learning, social cognition, cognitive development, comparison, analogical reasoning, and theory of mind
- Subject:
- Psychology
- Creator:
- Christian Hosos
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/09/2019
- Date Modified:
- 01/09/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Microkinetic modeling is a powerful tool for creating dynamic and quantitative descriptions of complex systems. These detailed mechanistic models compliment experimental techniques and provide an ability to achieve deeper insights into chemical processes where numerous intermediates are highly reactive and difficult to quantify in the laboratory. This thesis discusses the...
- Keyword:
- volatiles, autoxidation, ethyl linoleate, microkinetic modeling, and oil-based paint
- Subject:
- Materials Science and Engineering
- Creator:
- Lindsay Oakley
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/09/2019
- Date Modified:
- 01/09/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- The work presented in this dissertation examines the interplay between electron transfer reactions and electron spin in photoactive organic molecules. Organic compounds that undergo electron transfer reactions after absorbing light are important in natural photosynthesis, photobiology, and synthetic photovoltaics. These electron transfer reactions depend on the spin states of the...
- Keyword:
- electron transfer, spin chemistry, photochemistry, spectroscopy, radical pair, and EPR
- Subject:
- Chemistry
- Creator:
- Noah Elliott Horwitz
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/10/2019
- Date Modified:
- 01/10/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- As neuroscience seeks to understand larger, more complicated systems and behaviors, we will require neural recording techniques that can monitor the activity of neurons across the whole brain. The unparalleled data-storage capabilities of DNA, combined with fast, genetically encodable DNA polymerase-based sensors, would allow for "ticker tape"-like recordings of neurons...
- Keyword:
- Next-generation sequencing, DNA Polymerase, Dynamic Time Warping, Molecular recording, and Brain activity mapping
- Subject:
- Interdepartmental Neuroscience Program (NUIN)
- Creator:
- Thaddeus Rudas Cybulski
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/10/2019
- Date Modified:
- 01/10/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Chemical probes are versatile and unique tools for biomedical research. A chemical probe is simply a selective small-molecule modulator of protein function that allows the user to ask mechanistic and phenotypic questions about its molecular target in biochemical, cell-based or animal studies. Experiments involving selective inhibitors can help delineate key...
- Keyword:
- small molecules, kinases, chemical biology, isoforms, and natural product
- Subject:
- Chemistry
- Creator:
- Kristine Deibler
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/10/2019
- Date Modified:
- 01/29/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Contained in the following dissertation are detailed investigations regarding the thermodynamics of small molecule activation by metalloporphyrin complexes isolated within metal-organic frameworks (MOFs). Chapter 1 provides a description of the role metalloporphyrin complexes play in biological systems and the challenges associated with studying small molecule activation by metalloporphryin sites in...
- Keyword:
- Inorganic Chemistry
- Subject:
- Chemistry
- Creator:
- Audrey Theresa Gallagher
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/10/2019
- Date Modified:
- 01/10/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Methanobactins (Mbns) are a growing family of ribosomally produced, post-translationally modified natural products that exhibit a high affinity for copper. These compounds were initially identified in methanotrophic bacteria, which oxidize methane to methanol as their sole source of carbon. One of the key enzymes in this metabolic pathway, particulate methane...
- Keyword:
- Methanobactin, Biosynthesis, Copper homeostasis, Methanotrophy, Chalkophores, and Natural products
- Subject:
- Interdepartmental Biological Sciences (IBiS) Graduate Program
- Creator:
- Grace Eileen Kenney
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/10/2019
- Date Modified:
- 01/29/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Technology has advanced rapidly, especially in the twenty-first century, influencing our day-to-day life on unprecedented levels. Most such advances in technology are closely linked to, and often driven by, the discovery and design of new materials. It follows that the discovery of new materials can not only improve existing technologies...
- Keyword:
- Materials Discovery, Density Functional Theory, Electrochemistry, Energy Materials, and Batteries
- Subject:
- Materials Science and Engineering
- Creator:
- Soo Kim
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/10/2019
- Date Modified:
- 01/10/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- This dissertation looks at the consequences of three different government regulatory policies---the nondistribution constraint (which prohibits managers of nonprofit organizations from distributing profits generated by the nonprofit organization to themselves), the 100/0, 85/15, and 90/10 rules (which restrict the fraction of revenue for-profit colleges and universities can receive from Title...
- Keyword:
- Industrial Organization, Prohibition, Nonprofit Organizations, and Higher Education
- Subject:
- Economics
- Creator:
- Brent Travis Howe
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/10/2019
- Date Modified:
- 01/10/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- As a variety of social capital, scholars’ traditional understanding of a producer’s status is difficult to carry over from one market context to another. However, from organizations seeking to hire rainmakers away from competing organizations within the same markets to producers expanding their offerings into adjacent (and sometimes distant) markets,...
- Keyword:
- Status, Art market, and social signals
- Subject:
- Sociology
- Creator:
- Kangsan Lee
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/10/2019
- Date Modified:
- 01/30/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- This dissertation provides an account of the richest people in Glasgow and Liverpool at the end of the nineteenth and beginning of the twentieth centuries. It focuses on those in shipping, trade, and shipbuilding, who had global interests and amassed large fortunes. It examines the transition away from family business...
- Keyword:
- Glasgow, Family, Britain, Business, and Liverpool
- Subject:
- History
- Creator:
- Emma Elizabeth Goldsmith
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/11/2019
- Date Modified:
- 01/30/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- While synthesis and transformation processes to produce monodisperse nanoparticles are empirically well-developed, the pathways for these reactions as well as the exact role of synthetic agents and binding characteristics of surface moieties remain poorly understood. This lack of understanding is primarily due to the paucity of information about nanoparticle structural...
- Keyword:
- CTAB, in-situ, XAFS, nanocage, Galvanic exchange, and nanorods
- Subject:
- Materials Science and Engineering
- Creator:
- Liane Michelle Moreau
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/11/2019
- Date Modified:
- 01/11/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Small hydrocarbons and their oxygenated derivatives are critical to atmospheric organic aerosol formation and growth. Secondary organic aerosols (SOAs) constitute a significant portion of total atmospheric organic aerosols, and are often generated through the oxidation of biogenic volatile organic compounds (VOCs) such as isoprene, -pinene, and -caryophyllene. Interfaces of SOA...
- Keyword:
- aerosol, hydrocarbons, orientations, nonlinear optics, and computation
- Subject:
- Chemistry
- Creator:
- Hilary Marie Chase
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/11/2019
- Date Modified:
- 01/11/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Electromagnetic metamaterials composed of colloidally synthesized plasmonic metal nanoparticles offer new opportunities to probe light-matter interactions. The properties of these structures largely depend on the spatial arrangement of nanoparticles within them. Therefore, new assembly strategies that afford a high level of structural control are expected to enable a broad range...
- Keyword:
- DNA-mediated assembly, reconfigurable metamaterials, plasmonic nanoparticles, multicomponent nanoparticle architectures, and electromagnetic metamaterials
- Subject:
- Materials Science and Engineering
- Creator:
- Qingyuan Lin
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/11/2019
- Date Modified:
- 01/11/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Optical interferometry is a powerful technique which has been widely utilized for well over a century in making the world’s most precise measurements. By measuring how the interference between two waves is affected by a physical process, one can deduce the magnitude of this process. Because the wavelength of a...
- Keyword:
- Optics, Interferometry, Metrology, Lasers, and Dispersion
- Subject:
- Electrical Engineering
- Creator:
- Joshua Yablon
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/11/2019
- Date Modified:
- 01/11/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- The electronic spin state (S) of metal ions is fundamental to the performance of magnets, protein cofactors, and magnetic resonance imaging (MRI) contrast agents. The ability to manipulate the spin state of transition metals allows for the development of advanced materials with emergent properties. This following chapters will introduce two...
- Keyword:
- Spin Crossover, spin state, Magnetism, MRI, Double Exchange, and Iron
- Subject:
- Chemistry
- Creator:
- Alexandra I. Gaudette
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/11/2019
- Date Modified:
- 01/11/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Starting materials for natural products, ideally synthesized using low-cost, highly active and selective catalysts, are of great interest to the pharmaceutical industry. Relevant reactions include the synthesis of 1,2-dihydropyridines, reduction of ketones/aldehydes, cleavage of esters, and reduction of amides to amines. Hydroelementation is an important catalytic process that involves H-E...
- Keyword:
- Carbonyl reduction, Catalysis, Pyridine dearomatization, Hydroboration, and Organolanthanide
- Subject:
- Chemistry
- Creator:
- Victoria Lynn Weidner
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/11/2019
- Date Modified:
- 01/30/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- The renewed scholarly interest in the connections between taxation, state building efforts, and long-term economic development has revitalized the study of historical tax systems. How did today’s states initially acquire ‘fiscal capacity’, and why was this process more successful in some places than in others? Since African tax systems are...
- Keyword:
- colonialism, Africa, forced labor, and taxation
- Subject:
- History
- Creator:
- Marlous van Waijenburg
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/11/2019
- Date Modified:
- 01/30/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Certain inducible genes show faster reactivation if they were recently expressed. This epigenetic phenomenon is called transcriptional memory and is inherited for several generations after the first round of induction. During this phase, genes show several conserved molecular features that are essential for faster reactivation: peripheral localization of the gene,...
- Keyword:
- Epigenetic memory, Adaptive fitness, Genome organization, Evolution, Gene regulation, and GAL genes
- Subject:
- Interdepartmental Biological Sciences (IBiS) Graduate Program
- Creator:
- Varun Sood
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/11/2019
- Date Modified:
- 01/11/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- This dissertation consists of three essays in applied microeconomics. In the first chapter, I introduce a new statistical test for identifying prejudice from empirical data. In the second chapter, I (joint with James Schummer) consider the revenue maximization problem for a two-sided, one-to-one matching platform. In the third chapter, I...
- Keyword:
- matching, two-sided markets, media bias, test for prejudice, and economics of discrimination
- Subject:
- Managerial Economics and Strategy
- Creator:
- Phillip Louis Marx
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/16/2019
- Date Modified:
- 01/16/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- This dissertation uses several interrelated methods derived from corpus linguistics, statistics, and machine learning to infer a number of historically significant voice-leading schemas in a corpus of eighteenth-century Neapolitan solfeggi (exercises for voice with bass accompaniment). The goal of this work is to gain insights not only into the characteristics...
- Keyword:
- Galant style, Temporal regularity, Music cognition, Schema theory, Machine learning, and Structure mapping theory
- Subject:
- Music
- Creator:
- James Symons
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/16/2019
- Date Modified:
- 01/16/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- The study of tumor metabolism from the middle of the 20th century through the early 21st almost entirely ignored the mitochondria; instead, the field focused on cancer cells use of glycolysis even when oxygen was not limiting, termed aerobic glycolysis. Due to this observation, it was often speculated that malignant...
- Keyword:
- Outcomes and Biological
- Subject:
- Driskill Graduate Training Program in Life Sciences
- Creator:
- Samuel Edward Weinberg
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/16/2019
- Date Modified:
- 01/30/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- This dissertation explores a form of performance I call “ototheatre,” which is a mobile and participatory audience experience executed with portable sound technology. Ototheatre is an emergent artistic form that sits at a convergence of contemporary technologies and audience consumption habits. Case studies, including smartphone applications and new theatrical works...
- Keyword:
- audience participation, immersive theatre, mobile performance, augmented reality, soundwalk, and audio theatre
- Subject:
- Theatre and Drama
- Creator:
- Lauren Rachele Beck
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/16/2019
- Date Modified:
- 01/16/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- My research interests, which span organic, inorganic, physical and biochemistry, have focused broadly on photo-, magneto- and redox-active molecules, especially those with potential applications in organic photovoltaics, spintronics and electronics. My research under the joint supervision of Professor Wasielewski and Professor Fraser Stoddart has concentrated upon understanding electronic and magnetic...
- Keyword:
- Chemistry
- Subject:
- Chemistry
- Creator:
- Yilei Wu
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/16/2019
- Date Modified:
- 01/16/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- In his Nobel lecture Herbert Kroemer famously stated that “The interface is the device”. While he made this statement in the context of semiconducting heterostructures, it has proven to be just as relevant for more complex materials, such as the transition metal oxides. In particular, the 2-D conducting gas that...
- Keyword:
- Strongly Correlated Electrons, Low Temperature Physics, Electrical Anisotropy, Superconductivity, Electrical Transport, and Complex Oxides
- Subject:
- Applied Physics
- Creator:
- Samuel K. Davis
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/16/2019
- Date Modified:
- 01/16/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- In vivo, substantia nigra pars compacta (SNc) dopaminergic neurons exhibit three spiking patterns – irregular, regular, and bursting. These distinct modes of activity are thought to underlie the different roles that dopamine (DA) plays in target structures within the basal ganglia. In particular, burst spiking in SNc DA neurons is...
- Keyword:
- burst firing, pedunculopontine nucleus, substantia nigra pars compacta, dopamine, and glutamate
- Subject:
- Interdepartmental Neuroscience Program (NUIN)
- Creator:
- Daniel James Galtieri
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/16/2019
- Date Modified:
- 01/16/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- The promise of next-generation electronics, which combines features such as mechanical flexibility, optical transparency, and relatively low-cost, has stimulated tremendous research efforts during the past few years. As perhaps the most fundamental component of an electronic circuit, the design and optimization of the thin film transistor (TFT) is of great...
- Keyword:
- Characterization, X-ray, Thin Film, Metal Oxides, and Dielectrics
- Subject:
- Applied Physics
- Creator:
- Li Zeng
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/16/2019
- Date Modified:
- 01/16/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- In the near future, self-driving or driverless vehicles will operate without human control, enabling passengers to use their time in new ways. This opens up avenues for designing new interactions and experiences for individuals or groups traveling in an automobile. For that scenario, automobile manufacturers propose developing bigger and better...
- Keyword:
- self-driving cars
- Subject:
- Computer science and Autonomous vehicles
- Creator:
- Amartya Banerjee
- Owner:
- Chris Diaz
- Date Uploaded:
- 01/16/2019
- Date Modified:
- 01/16/2019
- Date Created:
- 2018
- Resource Type:
- Dissertation
-
- Description:
- Photovoltaic technology can help meet the exploding world energy demand in a sustainable and environmentally friendly way. Organic photovoltaics (OPVs) are especially attractive because they can be constructed with low-cost organic content and are amenable to high-throughput large-scale fabrication techniques. Synthetic modification of organic semiconductors has paved way for the...
- Keyword:
- Chemistry
- Subject:
- Chemistry
- Creator:
- Amod Timalsina
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/18/2019
- Date Modified:
- 01/30/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- The Pseudomonas aeruginosa type III secretion system delivers effector proteins directly into target cells, allowing the bacterium to modulate host cell functions. ExoU is the most cytotoxic of the known effector proteins and has been associated with more severe infections in humans. Previous studies have shown that ExoU is a...
- Keyword:
- Pseudomonas aeruginosa, ExoU, and oligomerization
- Subject:
- Driskill Graduate Training Program in Life Sciences
- Creator:
- Angelica Zhang
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/18/2019
- Date Modified:
- 01/18/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Most lubricants contain a series of additives that reduce friction and wear, and protect contacting surfaces. The design of these additives must be modernized to meet the challenges involved with high operating temperatures, extreme environmental conditions, and increasingly stringent environmental regulations. This research demonstrates three novel lubricant additive strategies that...
- Keyword:
- Additives, Wear, Lubrication, Friction, and Tribology
- Subject:
- Mechanical Engineering
- Creator:
- Blake Johnson
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/18/2019
- Date Modified:
- 01/18/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- This dissertation asks how a dynamic of vengeance involving the United States and anti-imperialist political organizations in the Middle East emerged and persisted between the 1967 Middle East war and the battle of Tora Bora in Afghanistan in December 2001. It tracks the construction of channels—ideological, institutional, emotional, and personal—through...
- Keyword:
- chains, channels, vengeance, anti-imperialism, national security, and Middle East
- Subject:
- History
- Creator:
- Alex Hobson
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/18/2019
- Date Modified:
- 01/30/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Of the thousands of planetary candidates discovered by the Kepler mission, roughly a third are in known multiple transiting-planet systems. High-multiplicity Kepler systems (referred to as Kepler Multis) are often tightly packed and may be on the verge of instability. Many systems of this type could have experienced past instabilities,...
- Keyword:
- planets and satellites, dynamical evolution and stability, gaseous planets, and hydrodynamics
- Subject:
- Physics and Astronomy
- Creator:
- Jason Hwang
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/18/2019
- Date Modified:
- 01/18/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- The Bcl-2 family is considered the guardian of the mitochondrial apoptotic pathway. While there are numerous endogenous Bcl-2 antagonists that share similar homology, structure, topology, and expression pattern, only the loss of Bim in mice is sufficient to lead to the development of a systemic autoimmunity. Even loss of both...
- Keyword:
- Apoptosis
- Subject:
- Driskill Graduate Training Program in Life Sciences
- Creator:
- FuNien Tsai
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/23/2019
- Date Modified:
- 01/23/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Many species have lost their natural habitat due to anthropogenic land use change. Ecologists are increasingly looking at habitat in cities to bolster efforts to conserve biodiversity. Green roofs are examples of urban habitats that are becoming more common globally. Green roofs can provide resources to support life in an...
- Keyword:
- Plant Biology and Conversation
- Subject:
- Plant Biology and Conversation
- Creator:
- Kelly Ksiazek Mikenas
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/23/2019
- Date Modified:
- 01/23/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Psychosocial stress is part of everyday life, and while ubiquitous, stress plays a huge role disease development and treatment. Though the stressor’s intensity, predictability, and frequency (acute vs chronic) are important determinants of disease development, interactions with one’s genetic and epigenetic make-up also play a causal role. Major Depressive Disorder...
- Keyword:
- coping, HCN, Hyperpolarization activated current, gastrointestinal motilit, stress, and mice
- Subject:
- Interdepartmental Neuroscience Program (NUIN)
- Creator:
- Daniel W. Fisher
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/23/2019
- Date Modified:
- 01/23/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Eosinophils are major effector cells in diseases including asthma, rhinitis, certain gastrointestinal disorders and atopic dermatitis. Current treatments include mediator antagonists and anti-inflammatory drugs that reduce allergic cell numbers and inhibit mediator release, but they are not fully effective or curative. On their surface, eosinophils selectively express Siglec-8 (sialic acid-binding...
- Keyword:
- Siglec-8, Eosinophils, Apoptosis, and Signaling
- Subject:
- Driskill Graduate Training Program in Life Sciences
- Creator:
- Daniela Janevska Carroll
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/23/2019
- Date Modified:
- 01/30/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- The expanding use of nanomaterials in consumer products challenges scientists to understand the impact of these materials before their inevitable release into the environment. In the same way that the widespread use of DDT and asbestos has caused unforeseen negative impacts on both the environment and on human health, the...
- Keyword:
- Nanomaterials, Sum Frequency Scattering, Sum Frequency Generation, Nano-Biointerface, and Nonlinear Optics
- Subject:
- Chemistry
- Creator:
- Laura Olenick
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/23/2019
- Date Modified:
- 01/23/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Keyword:
- Decentralized algorithms, Environmental estimation, Distributed algorithms, Environmental monitoring, and Swarm Robotics
- Subject:
- Mechanical Engineering
- Creator:
- Matthew L. Elwin
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/25/2019
- Date Modified:
- 01/25/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Many stroke survivors are left with residual movement impairments. Treating these impairments has proven difficult, because it is often unclear which mechanisms drive movement impairment. While the exact mechanisms are still uncertain, at present, evidence suggests that neuromuscular function is disrupted in two key domains following stroke: muscle biomechanics, and...
- Keyword:
- Motor Neurons, Stroke, Movement Disorders, Shear wave elastography, and Muscle
- Subject:
- Biomedical Engineering
- Creator:
- Andrew Lai
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/25/2019
- Date Modified:
- 01/25/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- The rodent whisker system is a widely used model to study the sense of touch. Its neuroanatomy parallels that of the human, but its mechanics are vastly simplified compared to that of the human tactile system. Just like other modalities with complex sensor accessory structures, the geometry, mechanics, and material...
- Keyword:
- rat, mouse, vibrissa, and seal
- Subject:
- Biomedical Engineering
- Creator:
- Hayley Belli
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/25/2019
- Date Modified:
- 01/30/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- This dissertation develops a framework to approach musical hybridity by considering style and genre interactions as an analytical layer of combinations of identities. It engages with the structural, contextual, and perceptual aspects of music by mixing perspectives from music studies with postcolonial studies, situated cognition, and genre studies. Hybridity is...
- Keyword:
- Hybridity, Analysis, Style and Genre, Music Theory, and Mixture
- Subject:
- Music
- Creator:
- Bruno Moschini Alcalde
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/25/2019
- Date Modified:
- 01/25/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- What follows is a strictly post-genomic dissertation. Over the past five years, I have strived to leave the nucleus behind, and even the endoplasmic reticulum and golgi apparatus. The human genome was sequenced over 15 years before the submission of this document, and the world changed somewhat less than anticipated—besides...
- Keyword:
- Top-Down Proteomics, Proteomics, Transplantation, Immunology, Mass Spectrometry, and Proteoforms
- Subject:
- Interdepartmental Biological Sciences (IBiS) Graduate Program
- Creator:
- Tinothy Toby
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/25/2019
- Date Modified:
- 01/25/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Literary critics typically oppose chronological and anachronistic historiographical schemes. In paired readings of early modern and contemporary poets, my dissertation, “The Shock of the Old: Periodization, Poetics, and Diachronic Exchange between the Renaissance and the Avant-Garde” investigates a series of poetic texts that defy this opposition. The poetic objects I...
- Keyword:
- diachronic, genre, Poetics, Queer, Periodization, and form
- Subject:
- English
- Creator:
- Toby Altman
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/25/2019
- Date Modified:
- 01/30/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation
-
- Description:
- Wind pollination has evolved from animal pollination at least 65 times in flowering plants, but the reverse transition is rare. Wind pollination is usually accompanied by the loss of traits that attract pollinators, and re-evolving them may be difficult. This dissertation examines this rare transition using Artocarpus (ca. 70 spp.,...
- Keyword:
- Chemical ecology, Moraceae, Phylogenetics, underutilized crops, tropical biology, and Pollination
- Subject:
- Plant Biology and Conversation
- Creator:
- Elliot M. Gardner
- Owner:
- Scholarly Digital Publishing
- Date Uploaded:
- 01/25/2019
- Date Modified:
- 01/25/2019
- Date Created:
- 2017-01-01
- Resource Type:
- Dissertation