For all its significance in world affairs, the United Nations is full of paradoxes. As a system - i.e. as a collection of independent yet interrelated entities - its contradictions derive from the juxtaposition of forces encouraging fragmentation and calls for improved harmonization. On its part, the reality of inter-organizational...
The vertebrate brain, which is made up of a vast array of individual neurons, is responsible for controlling numerous functions and behaviors, including distinguishing between visual cues, learning to navigate in a new environment, or making complex decisions. These neurons form specific networks that receive, process, and integrate chemical and...
I examine how consumers' purchase' decisions and intentions of purchases are affected by uncertainty about future deals (temporary price cuts or sales) for a product and how these results affect retailers' optimal pricing and marketing strategies. First I look at the effects of uncertainty about the timing of deals (i.e....
Magnetic resonance imaging (MRI) is an advanced imaging modality that is experiencing increasing popularity in clinical and experimental settings. MRI enjoys the benefit of high-resolution, the use of non-ionizing radiation, and the ability to distinguish between soft tissues. MR imaging is enhanced with the use of Gd3+ chelated contrast agents;...
As device sizes decrease, more functionality can be placed in an integrated circuit. Therefore, the design complexity of these circuits increases. To deal with complexity, designers move to higher abstraction levels. Currently, the highest abstraction level is the system-level. In our work we investigate the synthesis and verification problem at...
This dissertation studies whether stock mergers creates value for acquirers. The first chapter of this dissertation conducts a comprehensive review of the existing merger literature relevant to this topic. It includes existing merger theories, empirical studies on whether mergers are value destroying or value creating, and methodological issues on empirical...
Resource recovery is a promising category of polymer recycling where polymeric waste is converted via thermal or chemical means to monomer and chemical feedstocks. Specifically, pyrolysis is an attractive method because of its simplicity and ability to handle a heterogeneous feedstock. Polymer pyrolysis is characterized by a complex free radical...
End-Labeled Free-Solution Electrophoresis, or ELFSE, is an alternative strategy for DNA sequencing that proposes to eliminate the need for a viscous sieving matrix for size-based DNA separation. In this bioconjugate method, a perturbing entity or "drag-tag" is attached to differently sized DNA fragments produced by the Sanger reaction. This drag-tag...
This work explores the development and implementation of a biofilm model for multiple solid species and multiple dissolved components. The model makes use of several different advanced numerical methods in order to achieve the goal of describing the behavior of biofilms growing in wastewater treatment reactors. Using the model we...
Cardiovascular disease is a leading cause of morbidity and mortality worldwide. While many therapies have been used to treat vascular disease symptomatically, gene therapy offers a means of treating the molecular dysfunctions driving disease pathogenesis. Unfortunately, gene therapy has achieved only modest therapeutic success in clinical trials due to a...