Kainate receptors (KARs) are expressed throughout the central and peripheral nervous systems. One of three subfamilies of ionotropic glutamate receptors, KARs are localized both pre- and post-synaptically and exert important modulatory control over neural circuits. This modulatory role in circuit function makes them a potential actor in wide variety of...
Nano-structured mixed ionic and electronic conducting (MIEC) materials have garnered intense interest in electrode development for solid oxide fuel cells due to their high surface areas which allow for effective catalytic activity and low polarization resistances. In particular, composite solid oxide fuel cell (SOFC) cathodes consisting of ionic conducting scaffolds...
Fetal alcohol spectrum disorder (FASD), the result of fetal alcohol exposure (FAE), affects 2-11% of children worldwide with no treatments in sight. In my thesis work, I aimed to identify underlying biological mechanisms of the FAE-induced hippocampus-based cognitive deficits that would lead to identify potential treatment targets to reverse the...
Musicians have a responsibility to assess and perform new or extant music in order to present a larger body of repertoire to audiences. The purpose of this study is to introduce the euphonium music of the contemporary Belgian composer Frangois Glorieux to the tubaeuphonium community. With numerous works written for...
Classic mechanism design studies the implementation of optimal systems or processes in the presence of multiple selfish and fully rational agents. The theory of mechanism design has been one of the most celebrated advances in the economics discipline, especially with regards to auctions Myerson (1981),Vickrey (1961), Clarke (1971), Groves (1973)....
Glioblastoma multiforme (GBM) is the most prevalent primary central nervous system malignancy. Due to the aggressive nature of these tumors and our inability to adequately treat them, only 3-5% of patients survive longer than 3 years post-diagnosis. The standard of care for newly diagnosed GBM is surgical resection followed by...
In December 1928, Ernst Jünger wrote to his brother Friedrich Georg: “Wir müssen uns […] bemühen, die literarische Tätigkeit als Kriegsmittel zu betrachten.” This project analyzes the result of said activity: viz. text understood as a means of war. That is to say, it does not aim at answering questions...
X-ray reflectivity (XRR) versatile technique that characterize the surface structures. However, due to the lack of phase information of X-ray data, the reconstruction of electron density profile (EDP) from XRR data is an ill-posed inverse problem that requires extra attention. In Chapter 1, several key concepts in XRR data analysis...
A Dialogue on Nation-Building took place in Bishoftu, Ethiopia, on January 14-16, 2018. I was one of a dozen individuals invited to serve as resource persons for this meeting of over a hundred representatives from the government, civil society, political and faith-based organizations. The aim of the gathering was to...