Even though renal blood flow accounts for nearly a quarter of cardiac output, the renal medulla operates in an environment with a scant supply of oxygen. The reason for this apparent discrepancy is thought to be threefold. Blood flow to the outer medulla is less than 50% of that received...
Pattern recognition algorithms have been proposed as a way to control powered lower limb prostheses, specifically for transitioning between the different pre-programmed locomotion modes of the prosthesis (e.g., level ground walking, stair ascent, etc.). However, these algorithms cannot track changes in the statistical characteristics of input signals, and do not...
Myocardial perfusion is an important marker of cardiovascular health that is routinely evaluated clinically. Perfusion is measured most often using single photon emission computed tomography (SPECT) imaging, but magnetic resonance imaging (MRI) has many advantages over SPECT. Measuring perfusion quantitatively in ml/min/g would theoretically allow for improved characterization of cardiac...
Pattern recognition-based myoelectric control of upper limb prostheses has been made clinically available to individuals with more proximal upper limb amputations and can restore intuitive control of a prosthetic hand. This control method has yet to be implemented for individuals with amputations distal to the wrist (i.e. partial-hand amputations) and...
Stroke is the leading cause of death and long term disability in the industrialized world. With the current population aging, the number of individuals at risk of stroke along with the associated health care costs are anticipated to rise considerably in the coming years. Consequently, there is an unmet need...
It is becoming increasingly evident that the nanoscale organization and structure of macromolecules play a significant role in determining the function and properties of biological systems. To understand the relationships between biological structure and function at nanometer length scales, there is a need for methods which enable imaging of intact...