EGFR and cMET cross-talk is involved in breast cancer (BC) progression and resistance to different targeted therapies, however little is known about the co-expression patterns of EGFR and cMET or its prognostic significance in BC. Protein levels of EGFR, cMET and their phosphorylated proteins were measured in 825 BC samples...
Over the course of tumor growth, cancer cells interact with normal cells via processes that are difficult to understand by experiment alone. This challenge is particularly pronounced at early stages of tumor formation, when experimental observation is most limited. Eluci-dating such interactions could inform both understanding of cancer and clinical... and Tumor growth involves a dynamic interplay between cancer cells and host cells, which col-lectively form a tumor microenvironmental network that either suppresses or promotes tumor growth under different conditions. The transition from tumor suppression to tumor pro-motion is mediated by a tumor-induced shift in the local immune state, and despite...
The R package COPASutils provides a logical workflow for the reading, processing, and visualization of data obtained from the Union Biometrica Complex Object Parametric Analyzer and Sorter (COPAS) or the BioSorter large-particle flow cytometers. Data obtained from these powerful experimental platforms can be unwieldy, leading to difficulties in the ability...
We report on a diffusive analysis of the motion of flagellate protozoa species. These parasites are the etiological agents of neglected tropical diseases: leishmaniasis caused by Leishmania amazonensis and Leishmania braziliensis, African sleeping sickness caused by Trypanosoma brucei, and Chagas disease caused by Trypanosoma cruzi. By tracking the positions of...
Touch screen devices such as smartphones and tablets are now ubiquitous in the lives of American children. These devices permit very young children to engage interactively in an intuitive fashion with actions as simple as touching, swiping and pinching. Yet, we know little about the role these devices play in...
Researchers have proposed that the culture in which we are raised shapes the way that we attend to the objects and events that surround us. What remains unclear, however, is how early any such culturally-inflected differences emerge in development. Here, we address this issue directly, asking how 24-month-old infants from...
Artificial spin ice lattices have emerged as model systems for studying magnetic frustration in recent years. Most work to date has looked at periodic artificial spin ice lattices. In this paper, we observe frustration effects in quasicrystal artificial spin ice lattices that lack translational symmetry and contain vertices with different...
This short talk was a part of a panel, "Digital Literacy in the Classroom," organized by Ann Hanlon and Abigail Nye (University of Wisconsin-Milwaukee), and which included Harriett Green (University of Illinois Urbana Champaign), and myself, at the 2016 DLF Forum in Milwaukee, WI, on November 8, 2016.
The following short talk—an initial thinking-through and provocation from my recent reading—was presented at HASTAC 2014 in Lima, Peru, as part of the “Political Platforms: Software, Social Justice, and Designing for Change” panel, which included Beatrice Choi, Anne Cong-Huyen, Amanda Philips, and Tara McPherson (discussant).
This paper was presented on March, 28, 2015, at the Association for College and Research Libraries Conference in Portland, Oregon. Slides are also available for download. and Post-graduate internships, residencies, and fellowships have existed in research libraries since the 1930s, and have increasingly become a diversity recruitment and retention method of college and university libraries since the 1980s. These programs recruit recent graduates from Library and Information Science programs for training and specialization in some aspect of...