Chapter 1. Undergraduate Gender Diversity and Direction of Scientific Research (with Francesca Truffa) Can diversity lead to greater research focus on populations underrepresented in science? Diverse researchers can bring new questions and perspectives, but exposure to diversity may also inspire scientists, regardless of demographic identity, to pursue new topics. This...
This work is composed of two separate projects that contribute to the field’s understanding of Neisseria gonorrhoeae genetics and physiology. First, I showed that N. gonorrhoeae mounts a substantial transcriptional program in response to hydrogen peroxide (HP), a prominent reactive oxygen species (ROS) encountered during infection. We measured which strain...
Evolutionary theory predicts that reproduction entails energetic costs that detract from somatic maintenance, accelerating biological aging. In women, such ‘costs of reproduction’ (CoR) are thought to arise predominantly during pregnancy and lactation, while in men the physiological effects of the steroid hormone testosterone (T) are believed to be a major...
The high-temperature oxidation/reduction behaviors of iron and its oxides are important to a variety of energy conversion and storage technologies, such as the solid-oxide iron-air battery and chemical looping combustion. The useful lifetime of iron redox materials is limited, however, by structural degradation arising from (i) sintering, accelerated by phase...
Background: Cancer-related cognitive impairment (CRCI) is among the most frequently reported adverse events during and following cancer treatment. Between 17% to 75% of chemotherapy-treated cancer patients evidence long-term cognitive deficits as many as 20 years after treatment. The variability in prevalence and the mechanisms of persistent CRCI are not well...
Prions are self-perpetuating, alternative protein conformations associated with neurological diseases and normal cellular functions. Saccharomyces cerevisiae contains many endogenous prions – providing a powerful system to study prionization. Previously, the Li Lab demonstrated that Swi1, a component of the SWI/SNF chromatin-remodeling complex, can form the prion [SWI+]. A small region,...
Abstract The overall purpose of this paper is to reconsider the narrative usage and function of a literary phenomenon like ‘opposition/tension/contradiction.’ Throughout my analysis of Alain-Robbe Grillet’s La jalousie, Chloé Delaume’s J’habite dans la television and Jean Genet’s Le Balcon I was focused on investigating the use of this phenomenon...
A greater number of strategies in one’s coping repertoire (i.e., the number of diverse strategies used across stressors or use habitually across several situations) may be beneficial and a precursor to coping flexibly across situations (Bonnano & Burton, 2013). Indeed, previous studies have demonstrated a benefit of having larger number...
Human skin oils are significant scavengers of atmospheric oxidants in occupied indoor environments. Many techniques used to study gas-phase transformations of surface films indoors have been limited to off-line bulk analysis, although more surface-selective methodologies are emerging. Here, we present a multi-prong analytical approach to characterizing skin oil ozonolysis. Skin...
The Operating System (OS) kernel is a key component of modern computing infrastructure, yet it is prone to numerous vulnerabilities, many of which cause memory corruptions that can be exploited by attackers to perform malicious activities. While various techniques have been introduced to secure the Linux kernel, it still constantly...