Amyloid-β oligomers, also known as
amyloid-β derived diffusible ligands
(ADDLs), have been implicated in numerous
studies as being a possible cause for
Alzheimer’s disease (AD). The goal of this
study was to investigate the kinetics of the
oligomerization of the monomer amyloid-β
(Aβ) into ADDLs in various ratios of
dimethyl...
Surface patterns, formed by the coassembly
of cationic-anionic amphiphiles into
cylindrical micelles, were analyzed. The
competition between electrostatic forces
and the net incompatibility χ arising from
the different chemical natures of those
oppositely charged amphiphiles resulted in
the formation of segregated domains. These
surface domains are not macroscopically
segregated due...
The purpose of this study is to characterize
the nanometer-scale structure of an Al2O3-
W-Ge multilayer utilizing x-ray reflectivity.
Attributes such as layer thickness, density,
surface, and interface roughness are
determined and explained. The reasons for
using this particular multilayer are also
reviewed, as well as the benefits to science...
In this work, computational electrodynamics
is used to calculate extinction,
scattering, and local electric fields around
the transition metal nanoparticles. Rhodium
and ruthenium exhibit plasmon peak shifts
as a function of local refractive index
comparable to particles of silver and gold.1,2
In addition, the local fields calculated
indicate that Rh...
There is a continuing need for patterning
multifunctional materials to harness their
features and explore synergy among
diverse properties and phenomena. Soft
lithography, among various patterning
techniques, is a versatile method that can
generate inorganic patterns in a parallel
mode. Experimentation was performed
making use of flexible soft lithography to...
Carbon nanotubes have been shown to
behave as very effective conductors and
semiconductors, but their electronic uses
are limited by how well metallic and
semiconducting nanotubes can be sorted.
Recent investigations have shown an
effective method of separating laser
ablation–produced carbon nanotubes by
electronic type. However, laser ablation
nanotubes are...
Second harmonic generation (SHG),
a nonlinear optical tool, was used to
characterize DNA bound through a
chemical linker to the flat surface of a
hemispherical lens. Contact angle
measurements were used to guarantee
that the chemical linker did not hydrolyze
under experimental conditions. SHG
experiments followed the effects of salt...
Two-phase multiferroic nanostructures
have the potential to display magnetoelectricity
(ME) through interphase mechanical
coupling. Nanoscale ME-based technology
may lead to the next generation of computer
memory. In this research, soft electron
beam lithography (soft-eBL) was used to
fabricate submicron-sized structures of
cobalt ferrite (magnetostrictive) and barium
titanate (piezoelectric) as bottom...
Oligonucleotide-functionalized gold
nanoparticles (DNA-Au NPs) find
ubiquitous use in various biomolecular
detection schemes due to their unique
chemical and physical properties. This
study investigates the effects of nanoparticle
size and concentration of salt in
solution on the DNA loading of the Au NP
surface. The DNA loading studies are
performed...
The effects of volumetric size-control
techniques on the photoinduced conversion
of silver colloids to triangular nanoprisms
were examined. It was hoped that through
the application of size-control techniques
on photocatalyzed reactions, a new method
of controlling particle dimensions could
be established. Initial work focused on
optimizing the synthesis procedure in...