Drawing on over 400 legal decisions and other documentary materials, 40 semi-structured interviews with legal and scientific actors, and hundreds of hours of multi-sited ethnographic observation, I offer a fine-grained analysis of how expert evaluative practices become institutionalized in legal settings and result in divergent understandings of sexuality within the...
This dissertation explores topics in information economics. A particular focus in this dissertation is how competition affects incentives for information acquisition and information sharing between competitors. The first chapter studies a principal-agent setting where two principals compete for the services of one agent. The second chapter studies how competition in...
Advances in biosensor engineering have enabled the design of programmable molecular systems to detect a range of pathogens, nucleic acids, and chemicals. Here, we engineer and field-test a biosensor for fluoride, a major groundwater contaminant of global concern. The sensor consists of a cell-free system containing a DNA template that...
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are expressed in the heart and central nervous system where they regulate membrane excitability. Recently, inhibiting HCN channels in the hippocampus has been identified as a possible therapeutic intervention for the treatment of Major Depressive Disorder (MDD). However, based on the high expression level of...